Programmed and self-organized flow of information during morphogenesis

C Collinet, T Lecuit - Nature Reviews Molecular Cell Biology, 2021 - nature.com
How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

Proliferating active matter

O Hallatschek, SS Datta, K Drescher, J Dunkel… - Nature Reviews …, 2023 - nature.com
The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

Growth anisotropy of the extracellular matrix shapes a developing organ

S Harmansa, A Erlich, C Eloy, G Zurlo… - Nature …, 2023 - nature.com
Final organ size and shape result from volume expansion by growth and shape changes by
contractility. Complex morphologies can also arise from differences in growth rate between …

Chameleon-like elastomers with molecularly encoded strain-adaptive stiffening and coloration

M Vatankhah-Varnosfaderani, AN Keith, Y Cong… - Science, 2018 - science.org
Active camouflage is widely recognized as a soft-tissue feature, and yet the ability to
integrate adaptive coloration and tissuelike mechanical properties into synthetic materials …

Human brain organoids on a chip reveal the physics of folding

E Karzbrun, A Kshirsagar, SR Cohen, JH Hanna… - Nature physics, 2018 - nature.com
Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its
origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously …

Flexible and stretchable electrochemical sensors for biological monitoring

Y Zhao, KQ Jin, JD Li, KK Sheng… - Advanced …, 2023 - Wiley Online Library
The rise of flexible and stretchable electronics has revolutionized biosensor techniques for
probing biological systems. Particularly, flexible and stretchable electrochemical sensors …

Mechanochemical feedback loops in development and disease

E Hannezo, CP Heisenberg - Cell, 2019 - cell.com
There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Mechanics of morphological instabilities and surface wrinkling in soft materials: a review

B Li, YP Cao, XQ Feng, H Gao - Soft Matter, 2012 - pubs.rsc.org
Morphological instabilities and surface wrinkling of soft materials such as gels and biological
tissues are of growing interest to a number of academic disciplines including soft …

[HTML][HTML] Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling

JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson… - Cell stem cell, 2017 - cell.com
Gastric and small intestinal organoids differentiated from human pluripotent stem cells
(hPSCs) have revolutionized the study of gastrointestinal development and disease. Distal …

Villification: how the gut gets its villi

AE Shyer, T Tallinen, NL Nerurkar, Z Wei, ES Gil… - Science, 2013 - science.org
The villi of the human and chick gut are formed in similar stepwise progressions, wherein the
mesenchyme and attached epithelium first fold into longitudinal ridges, then a zigzag …