Gastroesophageal reflux disease (GERD) continues to be among the most common
diseases seen by gastroenterologists, surgeons, and primary care physicians. Our …

Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …

Gastroesophageal reflux disease (GERD) is a condition in which gastric contents regurgitate
into the esophagus or beyond, resulting in either troublesome symptoms or complications …

Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

Proton-pump inhibitors (PPIs) are the most effective therapy for the full spectrum of gastric-
acid-related diseases. However, in the past decade, a steadily increasing list of …

Preventing Gastrointestinal Bleeding in the Hospital Acid suppression is widely used to
lower the risk of gastrointestinal bleeding in critically ill patients, and the practice has spread …

Summary Background Proton pump inhibitors (PPIs) are widely used to treat and prevent
acid‐related disorders. Despite high efficacy, PPI safety has been increasingly scrutinised …

Clostridium (reclassified as “Clostridioides”) difficile infection (CDI) is a healthcare-
associated infection and significant source of potentially preventable morbidity, recurrence …

Background: Gut dysbiosis associated with the use of proton-pump inhibitors (PPIs) has
been found to lead to the occurrence of infectious and inflammatory adverse events. A …