During early development, the hindbrain is sub-divided into rhombomeres that underlie the
organisation of neurons and adjacent craniofacial tissues. A gene regulatory network of …

Hox genes play key roles in axial patterning and regulating the regional identity of cells and
tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox …

Metazoans differentially express multiple Hox transcription factors to specify diverse cell
fates along the developing anterior-posterior axis. Two challenges arise when trying to …

Gene duplication and divergence is a major contributor to the generation of morphological
diversity and the emergence of novel features in vertebrates during evolution. The …

Sertoli cells are essential for germ cell development and function. Their disruption by
endocrine disrupting chemicals (EDCs) or drugs could jeopardize spermatogenesis …

Neurogenic hypertension stems from an imbalance in autonomic function that shifts the
central cardiovascular control circuits toward a state of dysfunction. Using the female …

Histone lysine-specific methyltransferase 2 (KMT2A-D) proteins, alternatively called mixed
lineage leukemia (MLL1-4) proteins, mediate positive transcriptional memory. Acting as the …

The pathogenesis of many rare tumor types is poorly understood, preventing the design of
effective treatments. Solitary fibrous tumors (SFTs) are neoplasms of mesenchymal origin …

Hox genes play key roles in the anterior-posterior (AP) specification of all 3 germ layers
during different developmental stages. It is only partially understood how they function in …

For this Special Issue “2020 Feature Papers by JDB'Editorial Board Members,” we present a
collection of studies, including original research papers, and review articles by our …