Over the past decade, methods for predicting three-dimensional (3-D) chromosome and
genome structures have proliferated. This has been primarily due to the development of high …

Eukaryotic chromatin is a hierarchical collection of nucleoprotein structures that package
DNA to form chromosomes. The initial levels of packaging include folding of long strings of …

The mechanisms underlying gene repression and silencers are poorly understood. Here we
investigate the hypothesis that H3K27me3-rich regions of the genome, defined from clusters …

Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear,
concise manner to aid in the comprehension of this complex subject. Each technique …

Polymorphonuclear neutrophils have in recent years attracted new attention due to their
ability to release neutrophil extracellular traps (NETs). These web-like extracellular …

Sperm cells are remarkably complex and highly specialized compared to somatic cells.
Their function is to deliver to the oocyte the paternal genomic blueprint along with a pool of …

Here we propose a fluorescent sensor, Chroma-V, consisted of a Hoechst ligand (Hoe) to
target chromatin DNA and a BODIPY rotor (BDP) to sense the local viscosity that reflects …

The present study was designed to show the applicability of scanning ion conductance
microscopy (SICM) for imaging different types of biological samples. For this purpose, we …

The accuracy of the secondary structure element (SSE) identification from volumetric protein
density maps is critical for de‐novo backbone structure derivation in electron cryo …

In order to gain better understanding of the behavior of complex biological systems, it is
sometimes necessary to monitor biological samples in their native state and in their …