[HTML][HTML] The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

[HTML][HTML] Omega-3 fatty acids and cancer cell cytotoxicity: implications for multi-targeted cancer therapy

D D'Eliseo, F Velotti - Journal of clinical medicine, 2016 - mdpi.com
Cancer is a major disease worldwide. Despite progress in cancer therapy, conventional
cytotoxic therapies lead to unsatisfactory long-term survival, mainly related to development …

Omega‐3 polyunsaturated fatty acids: the way forward in times of mixed evidence

KH Weylandt, S Serini, YQ Chen, HM Su… - BioMed research …, 2015 - Wiley Online Library
Almost forty years ago, it was first hypothesized that an increased dietary intake of omega‐3
polyunsaturated fatty acids (PUFA) from fish fat could exert protective effects against several …

[HTML][HTML] Polyunsaturated fatty acids mediated regulation of membrane biochemistry and tumor cell membrane integrity

S Mukerjee, AS Saeedan, MN Ansari, M Singh - Membranes, 2021 - mdpi.com
Particular dramatic macromolecule proteins are responsible for various cellular events in our
body system. Lipids have recently recognized a lot more attention of scientists for …

[HTML][HTML] Fatty acids and membrane lipidomics in oncology: a cross-road of nutritional, signaling and metabolic pathways

C Ferreri, A Sansone, R Ferreri, J Amézaga, I Tueros - Metabolites, 2020 - mdpi.com
Fatty acids are closely involved in lipid synthesis and metabolism in cancer. Their amount
and composition are dependent on dietary supply and tumor microenviroment. Research in …

Diet and gut microbes act coordinately to enhance programmed cell death and reduce colorectal cancer risk

RS Chapkin, SL Navarro, MAJ Hullar… - Digestive diseases and …, 2020 - Springer
Diet is an important risk factor for colorectal cancer (CRC), and several dietary constituents
implicated in CRC are modified by gut microbial metabolism. Microbial fermentation of …

Omega-3 fatty acids, membrane remodeling and cancer prevention

NR Fuentes, E Kim, YY Fan, RS Chapkin - Molecular aspects of medicine, 2018 - Elsevier
Proteins are often credited as the macromolecule responsible for performing critical cellular
functions, however lipids have recently garnered more attention as our understanding of …

Shaping functional gut microbiota using dietary bioactives to reduce colon cancer risk

DV Seidel, MA Azcárate-Peril, RS Chapkin… - Seminars in cancer …, 2017 - Elsevier
Colon cancer is a multifactorial disease associated with a variety of lifestyle factors.
Alterations in the gut microbiota and the intestinal metabolome are noted during colon …

Remodelling of primary human CD4+ T cell plasma membrane order by n-3 PUFA

YY Fan, NR Fuentes, TY Hou, R Barhoumi… - British journal of …, 2018 - cambridge.org
Cell membrane fatty acids influence fundamental properties of the plasma membrane,
including membrane fluidity, protein functionality, and lipid raft signalling. Evidence suggests …

Fish oil supplementation during chemotherapy increases posterior time to tumor progression in colorectal cancer

CQ Camargo, MC Mocellin, JA Pastore Silva… - Nutrition and …, 2016 - Taylor & Francis
abstract The authors evaluated clinical outcomes during and after chemotherapy in
colorectal cancer patients supplemented with fish oil during the first 9 wk of treatment. Thirty …