In vitro methods for testing antiviral drugs
M Rumlová, T Ruml - Biotechnology advances, 2018 - Elsevier
Despite successful vaccination programs and effective treatments for some viral infections,
humans are still losing the battle with viruses. Persisting human pandemics, emerging and …
humans are still losing the battle with viruses. Persisting human pandemics, emerging and …
The association of viral proteins with host cell dynein components during virus infection
J Merino‐Gracia, MF García‐Mayoral… - The FEBS …, 2011 - Wiley Online Library
After fusion with the cellular plasma membrane or endosomal membranes, viral particles are
generally too large to diffuse freely within the crowded cytoplasm environment. Thus, they …
generally too large to diffuse freely within the crowded cytoplasm environment. Thus, they …
HIV-1 and M-PMV RNA nuclear export elements program viral genomes for distinct cytoplasmic trafficking behaviors
GM Pocock, JT Becker, CM Swanson, P Ahlquist… - PLoS …, 2016 - journals.plos.org
Retroviruses encode cis-acting RNA nuclear export elements that override nuclear retention
of intron-containing viral mRNAs including the full-length, unspliced genomic RNAs (gRNAs) …
of intron-containing viral mRNAs including the full-length, unspliced genomic RNAs (gRNAs) …
Transcriptome analysis of newt lens regeneration reveals distinct gradients in gene expression patterns
Regeneration of the lens in newts is quite a unique process. The lens is removed in its
entirety and regeneration ensues from the pigment epithelial cells of the dorsal iris via …
entirety and regeneration ensues from the pigment epithelial cells of the dorsal iris via …
[图书][B] Fields Virology: Fundamentals
Page 1 Fields VIROLOGY VOLUME 4: Fundamentals SEVENTH EDITION EDITORS-IN-CHIEF
Peter M. Howley David M. Knipe VOLUME ASSOCIATE EDITORS LW Enquist Jeffrey I. Cohen …
Peter M. Howley David M. Knipe VOLUME ASSOCIATE EDITORS LW Enquist Jeffrey I. Cohen …
The structure of myristoylated Mason-Pfizer monkey virus matrix protein and the role of phosphatidylinositol-(4, 5)-bisphosphate in its membrane binding
We determined the solution structure of myristoylated Mason-Pfizer monkey virus matrix
protein by NMR spectroscopy. The myristoyl group is buried inside the protein and causes a …
protein by NMR spectroscopy. The myristoyl group is buried inside the protein and causes a …
HIV-1 protease-induced apoptosis
M Rumlová, I Křížová, A Keprová, R Hadravová… - Retrovirology, 2014 - Springer
Background Apoptosis is one of the presumptive causes of CD4+ T cell depletion during HIV
infection and progression to AIDS. However, the precise role of HIV-1 in this process …
infection and progression to AIDS. However, the precise role of HIV-1 in this process …
[HTML][HTML] The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication
The role of the membrane protein (prM/M) in flavivirus life cycle remains unclear. Here, we
identified a cellular interactor to the 40-residue-long ectodomain of prM/M (ectoM) using a …
identified a cellular interactor to the 40-residue-long ectodomain of prM/M (ectoM) using a …
ESCRT‐II's involvement in HIV‐1 genomic RNA trafficking and assembly
B Ghoujal, MP Milev, L Ajamian, K Abel… - Biology of the …, 2012 - Wiley Online Library
Background information Several host proteins play crucial roles in the HIV‐1 replication
cycle. The endosomal sorting complex required for transport (ESCRT) exemplifies a large …
cycle. The endosomal sorting complex required for transport (ESCRT) exemplifies a large …
Human immunodeficiency virus type-1 gag and host vesicular trafficking pathways
H Chu, JJ Wang, P Spearman - HIV Interactions with Host Cell Proteins, 2009 - Springer
The Gag protein of HIV-1 directs the particle assembly process. Gag recruits components of
the cellular vesicular trafficking machinery in order to traverse the cytoplasm of the cell and …
the cellular vesicular trafficking machinery in order to traverse the cytoplasm of the cell and …