Asymmetry of tensile versus compressive elasticity and permeability contributes to the regulation of exchanges in collagen gels

J Cacheux, J Ordonez-Miranda, A Bancaud… - Science …, 2023 - science.org
The Starling principle describes exchanges between blood and tissues based on the
balance of hydrostatic and osmotic flows. However, the permeation properties of the main …

Deformation-dependent polydimethylsiloxane permeability measured using osmotic microactuators

AR Spitzer, SB Hutchens - Soft Matter, 2023 - pubs.rsc.org
In soft solids, large deformations significantly alter molecular structure and device geometry,
which can impact other properties. In the case of mass transport, an interplay between flux …

Predictive Modeling of Rheological Behavior in Semisolid Pharmaceutical Formulations Using Computational Tools.

JB Reolon, BK Hammerschmitt, MHM Sari… - Brazilian Archives of …, 2024 - SciELO Brasil
Topical treatments for skin conditions offer significant benefits, yet understanding the
rheological characteristics of semi-solid formulations is crucial, as they directly influence …

Mechanical Characterization of a Tunable 3-D Collagen-Hyaluronic Acid Hydrogel for Use in Cell Culture

J Tucker, V Lai - Recent Progress in Materials, 2024 - lidsen.com
Many cells demonstrate variances in behavior due to their cell culture environment. To
provide a mechanically-tunable, tissue-like environment, a 3D hydrogel for cell culture was …

Decoupling shear stress and pressure effects in the biomechanics of autosomal dominant polycystic kidney disease using a perfused kidney-on-chip

B Lapin, G Gropplero, J Vandensteen, M Mazloum… - …, 2024 - pmc.ncbi.nlm.nih.gov
Kidney tubular cells are submitted to two distinct mechanical forces generated by the urine
flow: shear stress and hydrostatic pressure. In addition, the mechanical properties of the …

Compressive forces induce epigenetic activation of aged human dermal fibroblasts through ERK signalling pathway

H Liu, L Yuan, L Baldi, TR Sornapudi, S GV - bioRxiv, 2024 - biorxiv.org
Age-related changes in human dermal fibroblasts (HDFs) contribute to impaired wound
healing and skin aging. While these changes result in altered mechanotransduction, the …