[HTML][HTML] Aging and diabetic retinopathy: Inherently intertwined pathophysiological processes

Q Li, M Wang, X Li, Y Shao - Experimental Gerontology, 2023 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness worldwide and a costly
complication of diabetes mellitus (DM). DR severity is associated with DM duration; thus, DR …

Senescent endothelial cells: a potential target for diabetic retinopathy

YL Liao, YF Fang, JX Sun, GR Dou - Angiogenesis, 2024 - Springer
Diabetic retinopathy (DR) is a diabetic complication that results in visual impairment and
relevant retinal diseases. Current therapeutic strategies on DR primarily focus on …

Diabetic retinopathy: a comprehensive update on in vivo, in vitro and ex vivo experimental models

MZ Sadikan, NA Abdul Nasir, L Lambuk… - BMC …, 2023 - Springer
Diabetic retinopathy (DR), one of the leading causes of visual impairment and blindness
worldwide, is one of the major microvascular complications in diabetes mellitus (DM) …

Diabetic retinopathy: emerging concepts of current and potential therapy

MZ Sadikan, NA Abdul Nasir - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
Diabetic retinopathy (DR) is one of the leading causes of permanent central blindness
worldwide. Despite the complexity and inadequate understanding of DR pathogenesis …

Therapeutic Investigation of Palm Oil Mill Effluent-Derived Beta-Carotene in Streptozotocin-Induced Diabetic Retinopathy via the Regulation of Blood–Retina Barrier …

Y Paramaswaran, A Subramanian, N Paramakrishnan… - Pharmaceuticals, 2023 - mdpi.com
Diabetic retinopathy (DR) primarily progresses into retinal degeneration caused by
microvascular dysfunction. The pathophysiology of DR progression is still uncertain. This …

Tocotrienol-rich fraction reduces retinal inflammation and angiogenesis in rats with streptozotocin-induced diabetes

MZ Sadikan, NA Abdul Nasir, NS Bakar… - … Medicine and Therapies, 2023 - Springer
Background Diabetic retinopathy (DR) is the second commonest microvascular complication
of diabetes mellitus. It is characterized by chronic inflammation and angiogenesis. Palm oil …

[HTML][HTML] The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma

F Latib, MAI Zafendi, MAM Lazaldin - Food Chemistry: Molecular Sciences, 2024 - Elsevier
Vitamin E, encompassing tocopherols and tocotrienols, is celebrated for its powerful
antioxidant properties, which help neutralize free radicals and protect cells from oxidative …

Scutellarin Alleviates Diabetic Retinopathy via the Suppression of Nucleotide-Binding Oligomerization Domain (NOD)-Like Receptor Pyrin Domain Containing Protein …

L Yang, Z Li, J Fang - Current Eye Research, 2024 - Taylor & Francis
Purpose Diabetic retinopathy, a prevalent complication of diabetes, represents the leading
cause of vision loss and blindness among middle-aged and elderly populations. Recent …

[HTML][HTML] Diabetes and the associated complications: The role of antioxidants in diabetes therapy and care

L Dilworth, D Stennett, A Facey, F Omoruyi… - Biomedicine & …, 2024 - Elsevier
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by high blood sugar
levels (hyperglycemia). Poorly managed diabetes can lead to complications affecting …

APX‑115A, a pan‑NADPH oxidase inhibitor, reduces the degree and incidence rate of dry eye in the STZ‑induced diabetic rat model

MH Noh, DK Lee, YS Kim, HY Kim… - Experimental and …, 2023 - spandidos-publications.com
Dye eye disease (DED) is a common ocular disorder in patients with diabetes. It has been
reported that APX‑115A, a pan‑nicotinamide adenine dinucleotide phosphate (NAPDH) …