[HTML][HTML] Hepatokines and metabolism: Deciphering communication from the liver
SO Jensen-Cody, MJ Potthoff - Molecular metabolism, 2021 - Elsevier
Background The liver is a key regulator of systemic energy homeostasis and can sense and
respond to nutrient excess and deficiency through crosstalk with multiple tissues. Regulation …
respond to nutrient excess and deficiency through crosstalk with multiple tissues. Regulation …
Insulin resistance in polycystic ovary syndrome: a systematic review and meta-analysis of euglycaemic–hyperinsulinaemic clamp studies
S Cassar, ML Misso, WG Hopkins, CS Shaw… - Human …, 2016 - academic.oup.com
STUDY QUESTION What is the degree of intrinsic insulin resistance (IR) in women with
polycystic ovary syndrome (PCOS) and the relative contribution of BMI to overall IR based …
polycystic ovary syndrome (PCOS) and the relative contribution of BMI to overall IR based …
A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis
Exercise training improves whole-body glucose homeostasis through effects largely
attributed to adaptations in skeletal muscle; however, training also affects other tissues …
attributed to adaptations in skeletal muscle; however, training also affects other tissues …
Lipocalin family proteins and their diverse roles in cardiovascular disease
The lipocalin (LCN) family members, a group of small extracellular proteins with 160-180
amino acids in length, can be detected in all kingdoms of life from bacteria to human beings …
amino acids in length, can be detected in all kingdoms of life from bacteria to human beings …
Maternal exercise improves glucose tolerance in female offspring
KI Stanford, H Takahashi, K So, AB Alves-Wagner… - Diabetes, 2017 - Am Diabetes Assoc
Poor maternal diet can lead to metabolic disease in offspring, whereas maternal exercise
may have beneficial effects on offspring health. In this study, we determined ifmaternal …
may have beneficial effects on offspring health. In this study, we determined ifmaternal …
Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice
PPARα (PPARA), expressed in most oxidative tissues, is a major regulator of lipid
homeostasis; hepatic PPARA plays a critical role during the adaptive fasting response by …
homeostasis; hepatic PPARA plays a critical role during the adaptive fasting response by …
Role of FXR in liver inflammation during nonalcoholic steatohepatitis
LE Armstrong, GL Guo - Current pharmacology reports, 2017 - Springer
Abstract Purpose of Review About 15–25% of patients with simple steatosis of nonalcoholic
fatty liver disease progresses to nonalcoholic steatohepatitis (NASH), and the underlying …
fatty liver disease progresses to nonalcoholic steatohepatitis (NASH), and the underlying …
The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation
Thermogenesis is an important contributor to whole-body energy expenditure and metabolic
homeostasis. Although circulating factors that promote energy expenditure are known …
homeostasis. Although circulating factors that promote energy expenditure are known …
NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action
The canonical inhibitor of nuclear factor κB kinase subunit β (IKK-β)–nuclear factor of κ light
polypeptide gene enhancer in B cells 1 (NF-κB1) pathway has been well documented to …
polypeptide gene enhancer in B cells 1 (NF-κB1) pathway has been well documented to …
Hepatokines: unveiling the molecular and cellular mechanisms connecting hepatic tissue to insulin resistance and inflammation
X Miao, A Alidadipour, V Saed, F Sayyadi, Y Jadidi… - Acta Diabetologica, 2024 - Springer
Insulin resistance arising from Non-Alcoholic Fatty Liver Disease (NAFLD) stands as a
prevalent global ailment, a manifestation within societies stemming from individuals' …
prevalent global ailment, a manifestation within societies stemming from individuals' …