The evolution of phenylpropanoid metabolism in the green lineage

T Tohge, M Watanabe, R Hoefgen… - Critical reviews in …, 2013 - Taylor & Francis
Phenolic secondary metabolites are only produced by plants wherein they play important
roles in both biotic and abiotic defense in seed plants as well as being potentially important …

Gene regulatory network reconstruction: harnessing the power of single-cell multi-omic data

D Kim, A Tran, HJ Kim, Y Lin, JYH Yang… - NPJ Systems Biology and …, 2023 - nature.com
Inferring gene regulatory networks (GRNs) is a fundamental challenge in biology that aims
to unravel the complex relationships between genes and their regulators. Deciphering these …

Multiscale embedded gene co-expression network analysis

WM Song, B Zhang - PLoS computational biology, 2015 - journals.plos.org
Gene co-expression network analysis has been shown effective in identifying functional co-
expressed gene modules associated with complex human diseases. However, existing …

GLay: community structure analysis of biological networks

G Su, A Kuchinsky, JH Morris, DJ States… - Bioinformatics, 2010 - academic.oup.com
GLay provides Cytoscape users an assorted collection of versatile community structure
algorithms and graph layout functions for network clustering and structured visualization …

Proteome profiling outperforms transcriptome profiling for coexpression based gene function prediction

J Wang, Z Ma, SA Carr, P Mertins, H Zhang… - Molecular & Cellular …, 2017 - ASBMB
Coexpression of mRNAs under multiple conditions is commonly used to infer cofunctionality
of their gene products despite well-known limitations of this" guilt-by-association"(GBA) …

Coexpression network analysis reveals an MYB transcriptional activator involved in capsaicinoid biosynthesis in hot peppers

B Sun, X Zhou, C Chen, C Chen, K Chen… - Horticulture …, 2020 - academic.oup.com
Plant biosynthesis involves numerous specialized metabolites with diverse chemical natures
and biological activities. The biosynthesis of metabolites often exclusively occurs in …

Comparing statistical methods for constructing large scale gene networks

JD Allen, Y Xie, M Chen, L Girard, G Xiao - PloS one, 2012 - journals.plos.org
The gene regulatory network (GRN) reveals the regulatory relationships among genes and
can provide a systematic understanding of molecular mechanisms underlying biological …

Comprehensive Evaluation and Transcriptome Analysis Reveal the Salt Tolerance Mechanism in Semi-Wild Cotton (Gossypium purpurascens)

Z Peng, A Rehman, X Li, X Jiang, C Tian… - International Journal of …, 2023 - mdpi.com
Elevated salinity significantly threatens cotton growth, particularly during the germination
and seedling stages. The utilization of primitive species of Gossypium hirsutum, specifically …

Targeted exploration and analysis of large cross-platform human transcriptomic compendia

Q Zhu, AK Wong, A Krishnan, MR Aure, A Tadych… - Nature …, 2015 - nature.com
We present SEEK (search-based exploration of expression compendia; http://seek.
princeton. edu/), a query-based search engine for very large transcriptomic data collections …

Genome-wide identification and functional prediction of nitrogen-responsive intergenic and intronic long non-coding RNAs in maize (Zea mays L.)

Y Lv, Z Liang, M Ge, W Qi, T Zhang, F Lin, Z Peng… - BMC genomics, 2016 - Springer
Background Nitrogen (N) is an essential and often limiting nutrient to plant growth and
development. Previous studies have shown that the mRNA expressions of numerous genes …