Small molecule based fluorescent chemosensors for imaging the microenvironment within specific cellular regions

J Yin, L Huang, L Wu, J Li, TD James… - Chemical Society Reviews, 2021 - pubs.rsc.org
The microenvironment (local environment), including viscosity, temperature, polarity,
hypoxia, and acidic-basic status (pH), plays indispensable roles in cellular processes …

Fluorescent probes for organelle-targeted bioactive species imaging

P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …

Small-molecule fluorescent probes for imaging and detection of reactive oxygen, nitrogen, and sulfur species in biological systems

X Jiao, Y Li, J Niu, X Xie, X Wang… - Analytical …, 2018 - pubmed.ncbi.nlm.nih.gov
Small-Molecule Fluorescent Probes for Imaging and Detection of Reactive Oxygen, Nitrogen,
and Sulfur Species in Biological Systems Small-Molecule Fluorescent Probes for Imaging and …

Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems

L Wu, J Liu, P Li, B Tang, TD James - Chemical Society Reviews, 2021 - pubs.rsc.org
In this tutorial review, we will explore recent advances for the design, construction and
application of two-photon excited fluorescence (TPEF)-based small-molecule probes. The …

Versatile fluorescent probes for imaging the superoxide anion in living cells and in vivo

H Xiao, W Zhang, P Li, W Zhang, X Wang… - Angewandte …, 2020 - Wiley Online Library
Abstract The superoxide anion (O2.−) is widely engaged in the regulation of cell functions
and is thereby intimately associated with the onset and progression of many diseases. To …

Fluorescent sensors for discriminative detection of multiple targets in pathological processes

C Yu, D Wu, L Dai, X He, JT Hou, J Shen, Z Li - Coordination Chemistry …, 2023 - Elsevier
The visualization of diseases is a crucial goal for clinicians as it aids in accurate diagnosis
and clinical surgery. In recent years, fluorescence sensors that exhibit optical changes in …

Deep-tissue fluorescence imaging study of reactive oxygen species in a tumor microenvironment

C Wu, Y Mao, X Wang, P Li, B Tang - Analytical Chemistry, 2021 - ACS Publications
Tumor microenvironment (TME) is the survival environment for tumor cells to proliferate and
metastasize in deep tissue. TME contains tumor cells, immune cells, stromal cells and a …

Advances in small-molecule fluorescent probes for the study of apoptosis

YX Ye, JC Pan, HC Wang, XT Zhang, HL Zhu… - Chemical Society …, 2024 - pubs.rsc.org
Apoptosis, as type I cell death, is an active death process strictly controlled by multiple
genes, and plays a significant role in regulating various activities. Mounting research …

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

MC Cabello, G Chen, MJ Melville, R Osman… - Chemical …, 2024 - ACS Publications
Reactive oxygen and nitrogen species are small reactive molecules derived from elements
in the air─ oxygen and nitrogen. They are produced in biological systems to mediate …

Cell organelles as targets of mammalian cadmium toxicity

WK Lee, F Thévenod - Archives of toxicology, 2020 - Springer
Ever increasing environmental presence of cadmium as a consequence of industrial
activities is considered a health hazard and is closely linked to deteriorating global health …