The inflammation-induced dysregulation of Reelin homeostasis hypothesis of Alzheimer's disease

BS Reive, V Lau… - Journal of …, 2024 - journals.sagepub.com
Alzheimer's disease (AD) accounts for most dementia cases, but we lack a complete
understanding of the mechanisms responsible for the core pathology associated with the …

Metabolic complications of psychotropic medications in psychiatric disorders: Emerging role of de novo lipogenesis and therapeutic consideration

MM Khan, ZA Khan, MA Khan - World Journal of Psychiatry, 2024 - pmc.ncbi.nlm.nih.gov
Although significant advances have been made in understanding the patho-physiology of
psychiatric disorders (PDs), therapeutic advances have not been very convincing. While …

The relationship of lifetime history of depression on the ovarian tumor immune microenvironment

CA Hathaway, MK Townsend, JR Conejo-Garcia… - Brain, Behavior, and …, 2023 - Elsevier
Background Depression is associated with a higher ovarian cancer risk. Prior work suggests
that depression can lead to systemic immune suppression, which could potentially alter the …

Association between polyunsaturated fatty acids and depression in women with infertility: a cross-sectional study based on the National Health and Nutrition …

Y Hong, X Jin, L Shi - Frontiers in Psychiatry, 2024 - frontiersin.org
Background Identifying possible influencing factors is crucial for the depression symptoms of
women experiencing infertility. This study aims to explore the association between …

[HTML][HTML] The role of estrogen across multiple disease mechanisms

X Xiang, P Palasuberniam, R Pare - Current Issues in Molecular Biology, 2024 - mdpi.com
Estrogen is a significant hormone that is involved in a multitude of physiological and
pathological processes. In addition to its pivotal role in the reproductive system, estrogen is …

Estrogen-immuno-neuromodulation disorders in menopausal depression

Y Zhang, X Tan, C Tang - Journal of Neuroinflammation, 2024 - Springer
A significant decrease in estrogen levels puts menopausal women at high risk for major
depression, which remains difficult to cure despite its relatively clear etiology. With the …

Association of age at menopause and suicide risk in postmenopausal women: a nationwide cohort study

DU Moon, H Kim, JH Jung, K Han, HJ Jeon - Frontiers in Psychiatry, 2024 - frontiersin.org
Introduction Early age at menopause has been linked to various adverse health outcomes,
but its association with suicide risk remains underexplored. This study aims to assess the …

Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS)

H Gao, X Zhai, Y Hu, H Wu - Scientific Reports, 2025 - nature.com
Progestogens commonly used in the clinic include levonorgestrel, etonogestrel,
medroxyprogesterone, hydroxyprogesterone, progesterone, desogestrel, and megestrol …

Does a program‐based cognitive behavioral therapy affect insomnia and depression in menopausal women? A randomized controlled trial

AH El‐Monshed, LM Khonji, M Altheeb… - … on Evidence‐Based …, 2024 - Wiley Online Library
Background Menopausal women often complain of a range of physical and psychological
symptoms known as menopausal syndrome. These symptoms are associated with …

Association between gynecological disorders and insomnia and depression trajectories: a longitudinal study of middle-aged women

H Zhong, F Zeng - Frontiers in Psychiatry, 2025 - frontiersin.org
Background Insomnia and depression often receive inadequate attention regarding their
association with common menopausal gynecological disorders (GDs), and there is a lack of …