Feature detection by retinal ganglion cells

D Kerschensteiner - Annual review of vision science, 2022 - annualreviews.org
Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …

[HTML][HTML] Dopamine signaling and myopia development: what are the key challenges

X Zhou, MT Pardue, PM Iuvone, J Qu - Progress in retinal and eye research, 2017 - Elsevier
In the face of an “epidemic” increase in myopia over the last decades and myopia
prevalence predicted to reach 2.5 billion people by the end of this decade, there is an urgent …

Unified classification of mouse retinal ganglion cells using function, morphology, and gene expression

J Goetz, ZF Jessen, A Jacobi, A Mani, S Cooler… - Cell reports, 2022 - cell.com
Classification and characterization of neuronal types are critical for understanding their
function and dysfunction. Neuronal classification schemes typically rely on measurements of …

Neurotoxic reactive astrocytes drive neuronal death after retinal injury

KA Guttenplan, BK Stafford, RN El-Danaf, DI Adler… - Cell reports, 2020 - cell.com
Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells
(RGCs) in the retina, often as a result of prolonged increases in intraocular pressure. We …

Melanopsin and the intrinsically photosensitive retinal ganglion cells: biophysics to behavior

MTH Do - Neuron, 2019 - cell.com
The mammalian visual system encodes information over a remarkable breadth of
spatiotemporal scales and light intensities. This performance originates with its complement …

Intrinsically photosensitive retinal ganglion cells: many subtypes, diverse functions

TM Schmidt, SK Chen, S Hattar - Trends in neurosciences, 2011 - cell.com
For decades, rods and cones were thought to be the only photoreceptors in the mammalian
retina. However, a population of atypical photoreceptive retinal ganglion cells (RGCs) …

Circadian rhythms, refractive development, and myopia

R Chakraborty, LA Ostrin, DL Nickla… - Ophthalmic and …, 2018 - Wiley Online Library
Purpose Despite extensive research, mechanisms regulating postnatal eye growth and
those responsible for ametropias are poorly understood. With the marked recent increases …

[HTML][HTML] Cell types and cell circuits in human and non-human primate retina

U Grünert, PR Martin - Progress in retinal and eye research, 2020 - Elsevier
This review summarizes our current knowledge of primate including human retina focusing
on bipolar, amacrine and ganglion cells and their connectivity. We have two main …

Eye smarter than scientists believed: neural computations in circuits of the retina

T Gollisch, M Meister - Neuron, 2010 - cell.com
We rely on our visual system to cope with the vast barrage of incoming light patterns and to
extract features from the scene that are relevant to our well-being. The necessary reduction …

Intrinsically photosensitive retinal ganglion cells

MTH Do, KW Yau - Physiological reviews, 2010 - journals.physiology.org
Life on earth is subject to alternating cycles of day and night imposed by the rotation of the
earth. Consequently, living things have evolved photodetective systems to synchronize their …