[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site

EI Vrettos, G Mező, AG Tzakos - Beilstein journal of organic …, 2018 - beilstein-journals.org
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …

Application of molecular dynamics simulations in the analysis of cyclodextrin complexes

AH Mazurek, Ł Szeleszczuk, T Gubica - International journal of molecular …, 2021 - mdpi.com
Cyclodextrins (CDs) are highly respected for their ability to form inclusion complexes via
host–guest noncovalent interactions and, thus, ensofance other molecular properties …

Smart multifunctional UiO-66 metal–organic framework nanoparticles with outstanding drug-loading/release potential for the targeted delivery of quercetin

M Parsaei, K Akhbari - Inorganic Chemistry, 2022 - ACS Publications
Herein, UiO-66 and its two functional analogs (with− NO2 and− NH2 functional groups) were
synthesized, and their potential ability as pH stimulus nanocarriers of quercetin (QU), an …

[HTML][HTML] Quercetin, rutin and quercetin-rutin incorporated hydroxypropyl β-cyclodextrin inclusion complexes

E Başaran, AA Öztürk, B Şenel, M Demirel… - European journal of …, 2022 - Elsevier
Quercetin (Q) and rutin (R) are well known and most studied flavonoids due to their activities
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …

Quercetin: a potential polydynamic drug

N Georgiou, MG Kakava, EA Routsi, E Petsas… - Molecules, 2023 - mdpi.com
The study of natural products as potential drug leads has gained tremendous research
interest. Quercetin is one of those natural products. It belongs to the family of flavonoids and …

Preparation and biophysical characterization of quercetin inclusion complexes with β-cyclodextrin derivatives to be formulated as possible nose-to-brain quercetin …

K Manta, P Papakyriakopoulou… - Molecular …, 2020 - ACS Publications
Quercetin (Que) is a flavonoid associated with high oxygen radical scavenging activity and
potential neuroprotective activity against Alzheimer's disease. Que's oral bioavailability is …

[HTML][HTML] Drug delivery based pharmacological enhancement and current insights of quercetin with therapeutic potential against oral diseases

Y Wang, B Tao, Y Wan, Y Sun, L Wang, J Sun… - Biomedicine & …, 2020 - Elsevier
The heavy burden of oral diseases such as oral cancers, dental caries, periodontitis, etc.
and their consequence on the patient's quality of life demonstrated an urgent demand for …

Redox properties of individual quercetin moieties

E Heřmánková, M Zatloukalová, M Biler… - Free Radical Biology …, 2019 - Elsevier
Quercetin is one of the most prominent and widely studied flavonoids. Its oxidation has been
previously investigated only indirectly by comparative analyses of structurally analogous …

A Review of Applications of Solid-State Nuclear Magnetic Resonance (ssNMR) for the Analysis of Cyclodextrin-Including Systems

AH Mazurek, Ł Szeleszczuk - International Journal of Molecular Sciences, 2023 - mdpi.com
Cyclodextrins, cyclic oligosaccharides composed of five or more α-D-glucopyranoside units
linked by α-1, 4 glycosidic bonds, are widely used both in their native forms as well as the …

Preparation and characterization of a nano-inclusion complex of quercetin with β-cyclodextrin and its potential activity on cancer cells

R Rajamohan, S Ashokkumar, K Murugavel, YR Lee - Micromachines, 2023 - mdpi.com
Quercetin (QRC), a flavonoid found in foods and plants such as red wine, onions, green tea,
apples, and berries, possesses remarkable anti-inflammatory and antioxidant properties …