Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer

L Buscail, B Bournet, P Cordelier - Nature reviews Gastroenterology & …, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is predicted to be the second most common
cause of death within the next 10 years. The prognosis for this disease is poor despite …

Liquid biopsy approach for pancreatic ductal adenocarcinoma

E Buscail, C Maulat, F Muscari, L Chiche, P Cordelier… - Cancers, 2019 - mdpi.com
Pancreatic cancer is a public health problem because of its increasing incidence, the
absence of early diagnostic tools, and its aggressiveness. Despite recent progress in …

Targeted detection of single-nucleotide variations: progress and promise

A Abi, A Safavi - ACS sensors, 2019 - ACS Publications
Advances in nucleic acid sequencing and genotyping technologies have facilitated the
discovery of an increasing number of single-nucleotide variations (SNVs) associated with …

Technological challenges and future issues for the detection of circulating microRNAs in patients with cancer

J Cacheux, A Bancaud, T Leichlé, P Cordelier - Frontiers in Chemistry, 2019 - frontiersin.org
In the era of precision medicine, the success of clinical trials, notably for patients diagnosed
with cancer, strongly relies on biomarkers with pristine clinical value but also on robust and …

Ferrocene-labeled and purification-free electrochemical biosensor based on ligase chain reaction for ultrasensitive single nucleotide polymorphism detection

F Hu, W Zhang, W Meng, Y Ma, X Zhang, Y Xu… - Analytica chimica …, 2020 - Elsevier
Single nucleotide polymorphisms (SNPs) are crucial during the early diagnosis of a given
disease as well as in evaluating their response to certain drugs. Thus, this study sought the …

The Role of Nanomaterials in Diagnosis and Targeted Drug Delivery

E Veg, K Hashmi, S Raza, S Joshi… - Chemistry & …, 2025 - Wiley Online Library
Nanomaterials have evolved into the most useful resources in all spheres of life. Their small
size imparts them with unique properties and they can also be designed and engineered …

Nanotechnology-based biosensors in drug delivery

MK Yazdi, P Zarrintaj, B Bagheri, YC Kim… - … for advanced drug …, 2020 - Elsevier
Nanotechnology-driven strategies have enabled scientists and engineers to fabricate
diverse drug delivery and (bio) sensor platforms. It is now possible to develop nanoscale …

Polyelectrolyte surface diffusion in a nanoslit geometry

GT Morrin, DF Kienle, JS Weltz, JC Traeger… - …, 2020 - ACS Publications
The surface diffusion of poly-l-lysine (PLL) in a planar nanoslit was studied using convex
lens-induced confinement (CLiC) single-molecule tracking microscopy. Three surface …

Direct in situ and real-time visualization of salt-dependent thiolated-DNA immobilization and biosensing on gold in nanofluidic channels

DK Yang, LK Yu, CT Kuo, JH Weng, T Leïchlé… - Sensors and Actuators B …, 2023 - Elsevier
Thiol-gold (Au) conjugation is perhaps the most routinely applied surface chemistry
approach to immobilize receptors within Au-based molecular sensing platforms. However …

Optical sensing analysis of bilayer porous silicon nanostructure

D Ge, J Shi, J Wei, L Zhang, Z Zhang - Journal of Physics and Chemistry of …, 2019 - Elsevier
Bilayer porous silicon (PSi) nanostructure is proposed as a biosensor by considering the
optical performance. The sensitivity of this bilayer PSi nanostructure with triangular lattice is …