Introduction: Statins reduce the risk of cardiovascular morbidity and mortality in patients with
or at risk for cardiovascular disease and their use is expanding, especially in elderly. Statins …

In the recent years, there have been an increasing number of reports on favourable effects of
statins in patients with advanced chronic liver disease. These include reduction in portal …

Background & Aims The combination of β-blockers and band ligation is the standard
approach to prevent variceal rebleeding, but bleeding recurs and mortality is high. The lipid …

Statins are effective drugs to reduce cardiovascular events secondary to dyslipidemia;
however, they cause frequent undesirable side effects. The incidence of statin-induced …

Solute carrier (SLC) family transporters utilize an electrochemical potential difference or an
ion gradient generated by primary active transporters for transporting their substrates across …

Purpose To aid prescribers in assessing a patient's risk for statin-induced myopathy (SIM),
we performed a comprehensive review of currently known risk factors and calculated …

This meta-analysis was conducted to determine the genotypic effects of rs4149056 and
rs2306283 polymorphism in SLCO1B1 gene on myopathy in patients with statin. Studies …

Statins, a class of lipid-lowering medications, have been a keystone treatment in
cardiovascular health. However, adverse effects associated with statin use impact patient …

Statin therapy reduces cardiovascular events in patients with, or at risk of, atherosclerotic
cardiovascular disease. However, statins are underutilized in patients for whom they are …

Numerous studies have illustrated the relationship between SLCO1B1 T521C polymorphism
and statin-induced myopathy risk; however, this association is not consistent. Three …