Wound healing occurs as a response to disruption of the epidermis and dermis. It is an
intricate and well-orchestrated response with the goal to restore skin integrity and function …

Keloids are abnormal scars that cause significant emotional and physical distress in patients
when inadequately treated. Keloid formation is theorized to occur as a result of an …

Hypertrophic scars and keloids can have significant detrimental effects on patients both
psychosocially and functionally. A careful identification of patient risk factors and a …

Keloids are pathological scars that grow over time and extend beyond the initial site of injury
after impaired wound healing. These scars frequently recur and rarely regress. They are …

Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Hypertrophic scars and keloids are caused by excessive tissue response to dermal injury
due to local fibroblast proliferation and collagen overproduction. This response occurs …

Objectives: Explain the causes of keloid formation. Describe the most common populations
that develop keloid formation. Review the signs and symptoms of keloids. Outline the …

While normal, controlled wound-healing results in scars that are nearly imperceptible,
hypertrophic scars (HTS) and keloids are the result of an abnormal wound-healing process …

Skin injury always results in fibrotic, non-functional scars in adults. Although multiple factors
are well-known contributors to scar formation, the precise underlying mechanisms remain …

Scars are an inevitable natural outcome of most wound healing processes and affect skin
functions, leading to cosmetic, psychological and social problems. Several strategies …