[HTML][HTML] Machine learning based brain signal decoding for intelligent adaptive deep brain stimulation

T Merk, V Peterson, R Köhler, S Haufe… - Experimental …, 2022 - Elsevier
Sensing enabled implantable devices and next-generation neurotechnology allow real-time
adjustments of invasive neuromodulation. The identification of symptom and disease …

Machine learning for adaptive deep brain stimulation in Parkinson's disease: closing the loop

AM Oliveira, L Coelho, E Carvalho… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disease bearing a
severe social and economic impact. So far, there is no known disease modifying therapy …

Deep brain stimulation creates informational lesion through membrane depolarization in mouse hippocampus

E Lowet, K Kondabolu, S Zhou, RA Mount… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) is a promising neuromodulation therapy, but the
neurophysiological mechanisms of DBS remain unclear. In awake mice, we performed high …

Implantable pulse generators for deep brain stimulation: challenges, complications, and strategies for practicality and longevity

C Sarica, C Iorio-Morin, DH Aguirre-Padilla… - Frontiers in Human …, 2021 - frontiersin.org
Deep brain stimulation (DBS) represents an important treatment modality for movement
disorders and other circuitopathies. Despite their miniaturization and increasing …

Landscape and future directions of machine learning applications in closed-loop brain stimulation

AS Chandrabhatla, IJ Pomeraniec, TM Horgan… - NPJ Digital …, 2023 - nature.com
Brain stimulation (BStim) encompasses multiple modalities (eg, deep brain stimulation,
responsive neurostimulation) that utilize electrodes implanted in deep brain structures to …

Electrocorticography is superior to subthalamic local field potentials for movement decoding in Parkinson's disease

T Merk, V Peterson, WJ Lipski, B Blankertz, RS Turner… - Elife, 2022 - elifesciences.org
Brain signal decoding promises significant advances in the development of clinical brain
computer interfaces (BCI). In Parkinson's disease (PD), first bidirectional BCI implants for …

[HTML][HTML] Neural interface systems with on-device computing: machine learning and neuromorphic architectures

J Yoo, M Shoaran - Current opinion in biotechnology, 2021 - Elsevier
Highlights•Neural interfaces continue to improve in channel count and form factor.•Low-
power machine learning and neuromorphic processors can be integrated onto neural …

Closed-loop neural prostheses with on-chip intelligence: A review and a low-latency machine learning model for brain state detection

B Zhu, U Shin, M Shoaran - IEEE transactions on biomedical …, 2021 - ieeexplore.ieee.org
The application of closed-loop approaches in systems neuroscience and therapeutic
stimulation holds great promise for revolutionizing our understanding of the brain and for …

[HTML][HTML] Wearable sensor-driven responsive deep brain stimulation for essential tremor

S Cernera, JD Alcantara, E Opri, JN Cagle, RS Eisinger… - Brain Stimulation, 2021 - Elsevier
Background Deep brain stimulation (DBS) is an effective surgical therapy for individuals with
essential tremor (ET). However, DBS operates continuously, resulting in adverse effects …

[HTML][HTML] Neuronal oscillations predict deep brain stimulation outcome in Parkinson's disease

J Hirschmann, A Steina, J Vesper, E Florin, A Schnitzler - Brain Stimulation, 2022 - Elsevier
Background Neuronal oscillations are linked to symptoms of Parkinson's disease. This
relation can be exploited for optimizing deep brain stimulation (DBS), eg by informing a …