Addressing barriers in comprehensiveness, accessibility, reusability, interoperability and reproducibility of computational models in systems biology

A Niarakis, D Waltemath, J Glazier… - Briefings in …, 2022 - academic.oup.com
Computational models are often employed in systems biology to study the dynamic
behaviours of complex systems. With the rise in the number of computational models, finding …

A roadmap for delivering a human musculoskeletal cell atlas

M Baldwin, CD Buckley, F Guilak, P Hulley… - Nature Reviews …, 2023 - nature.com
Advances in single-cell technologies have transformed the ability to identify the individual
cell types present within tissues and organs. The musculoskeletal bionetwork, part of the …

Waxholm Space atlas of the rat brain: A 3D atlas supporting data analysis and integration

H Kleven, IE Bjerke, F Clascá, HJ Groenewegen… - Nature …, 2023 - nature.com
Volumetric brain atlases are increasingly used to integrate and analyze diverse
experimental neuroscience data acquired from animal models, but until recently a publicly …

Is neuroscience FAIR? A call for collaborative standardisation of neuroscience data

JB Poline, DN Kennedy, FT Sommer, GA Ascoli… - Neuroinformatics, 2022 - Springer
In this perspective article, we consider the critical issue of data and other research object
standardisation and, specifically, how international collaboration, and organizations such as …

Toxicology knowledge graph for structural birth defects

JE Evangelista, DJB Clarke, Z Xie, GB Marino… - Communications …, 2023 - nature.com
Background Birth defects are functional and structural abnormalities that impact about 1 in
33 births in the United States. They have been attributed to genetic and other factors such as …

Correcting bias in cardiac geometries derived from multimodal images using spatiotemporal mapping

D Zhao, CA Mauger, K Gilbert, VY Wang, GM Quill… - Scientific Reports, 2023 - nature.com
Cardiovascular imaging studies provide a multitude of structural and functional data to better
understand disease mechanisms. While pooling data across studies enables more powerful …

Tissue registration and exploration user interfaces in support of a human reference atlas

K Börner, A Bueckle, BW Herr, LE Cross… - Communications …, 2022 - nature.com
Seventeen international consortia are collaborating on a human reference atlas (HRA), a
comprehensive, high-resolution, three-dimensional atlas of all the cells in the healthy human …

A Narrative Review of Personalized Musculoskeletal Modeling Using the Physiome and Musculoskeletal Atlas Projects

J Fernandez, V Shim, M Schneider… - Journal of Applied …, 2023 - journals.humankinetics.com
In this narrative review, we explore developments in the field of computational
musculoskeletal model personalization using the Physiome and Musculoskeletal Atlas …

[HTML][HTML] Biomechanical constitutive modeling of the gastrointestinal tissues: a systematic review

B Patel, A Gizzi, J Hashemi, Y Awakeem, H Gregersen… - Materials & …, 2022 - Elsevier
The gastrointestinal (GI) tract is a continuous channel through the body that consists of the
esophagus, the stomach, the small intestine, the large intestine, and the rectum. Its primary …

Organization and morphology of calcitonin gene‐related peptide‐immunoreactive axons in the whole mouse stomach

J Ma, D Nguyen, J Madas, A Bizanti… - Journal of …, 2023 - Wiley Online Library
Nociceptive afferent axons innervate the stomach and send signals to the brain and spinal
cord. Peripheral nociceptive afferents can be detected with a variety of markers (eg …