Detection technologies in proteome analysis

WF Patton - Journal of Chromatography B, 2002 - Elsevier
Common strategies employed for general protein detection include organic dye, silver stain,
radiolabeling, reverse stain, fluorescent stain, chemiluminescent stain and mass …

Combined x-ray and optical tomographic imaging system

WI Yared - US Patent 10,064,584, 2018 - Google Patents
The invention relates to a combined x-ray and optical (light-based) tomographic imaging
system that provides functional information at greater resolution than can be achieved by …

Rainbow's end: the quest for multiplexed fluorescence quantitative analysis in proteomics

WF Patton, JM Beechem - Current opinion in chemical biology, 2002 - Elsevier
During the past two years, the performance of fluorescence-based protein detection
methods has demonstrably eclipsed conventional technologies such as colloidal …

Modified carbocyanine dyes and their conjugates

WY Leung, CY Cheung, S Yue - US Patent 6,977,305, 2005 - Google Patents
Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is
Substituted at the 3-position by a reactive group or by a conjugated Substance, and their …

Modified carbocyanine dyes and their conjugates

WY Leung, CY Cheung, S Yue - US Patent 6,974,873, 2005 - Google Patents
3,864,644 A 2/1975 Lincoln et al. WO WO 2000/31534* 6/2000 4,011,086 A 3/1977 Simson
WO WO 01/02374. A1 1/2001 4,711.955 A 12/1987 Ward et al. WO WO 01/21624 3/2001 …

Proteome analysis of Saccharomyces cerevisiae under metal stress by two‐dimensional differential gel electrophoresis

YI Hu, G Wang, GYJ Chen, XIN Fu, SQ Yao - Electrophoresis, 2003 - Wiley Online Library
The defense mechanism by which cells combat metal stress remains poorly understood. By
utilizing a newly developed technique–the differential gel electrophoresis (DIGE)–we …

Oligosaccharide modification and labeling of proteins

B Agnew, SB Corry, KR Gee - US Patent 8,716,033, 2014 - Google Patents
The present invention generally relates to methods of func tionalizing proteins, particularly
antibodies, at oligosaccha ride linkages, methods of humanizing antibodies by modify ing …

Biocompatible fluorescent metal oxide nanoparticles

K Groves, M Rajopadhye - US Patent 9,913,917, 2018 - Google Patents
The invention relates to highly fluorescent metal oxide nanoparticles to which biomolecules
and other compounds can be chemically linked to form biocompatible, stable optical …

Antibody complexes and methods for immunolabeling

J Beechem, D Hagen, I Johnson - US Patent App. 10/666,291, 2007 - Google Patents
The present invention provides labeling reagents and meth ods for labeling primary
antibodies and for detecting a target in a sample using an immuno-labeled complex that …

Fluorescent imaging agents

M Rajopadhye, K Groves, DV Preda - US Patent 8,815,214, 2014 - Google Patents
US8815214B2 - Fluorescent imaging agents - Google Patents US8815214B2 - Fluorescent
imaging agents - Google Patents Fluorescent imaging agents Download PDF Info …