From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning

LS Li, L Yang, L Zhuang, ZY Ye, WG Zhao… - Military Medical …, 2023 - Springer
Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB).
Although the tuberculin skin test and interferon-gamma release assay can be used to …

Evaluating the diagnostic accuracy of QIAreach QuantiFERON-TB compared to QuantiFERON-TB Gold Plus for tuberculosis: a systematic review and meta-analysis

S Mahmoudi, S Nourazar - Scientific Reports, 2024 - nature.com
Accurate tuberculosis (TB) diagnosis remains challenging, especially in resource-limited
settings. This study aims to assess the diagnostic performance of the QIAreach …

Tuberculosis Immunoreactivity Surveillance in Malawi (Timasamala)—A protocol for a cross-sectional Mycobacterium tuberculosis immunoreactivity survey in …

HM Rickman, MD Phiri, HRA Feasey, H Mbale… - Plos one, 2024 - journals.plos.org
Tuberculosis (TB) transmission and prevalence are dynamic over time, and heterogeneous
within populations. Public health programmes therefore require up-to-date, accurate …

Tuberculosis Preventive Treatment in High TB-Burden Settings: A State-of-the-Art Review

V Chihota, M Gombe, A Gupta, N Salazar-Austin… - Drugs, 2024 - Springer
Tuberculosis (TB) is the leading cause of death from a single infectious agent. The burden is
highest in some low-and middle-income countries. One-quarter of the world's population is …

Building a model for the differential diagnosis of non-tuberculous mycobacterial lung disease and pulmonary tuberculosis: A case-control study based on …

Q Liu, X Pan, H An, J Du, X Li, W Sun, Y Gao… - International …, 2023 - Elsevier
Background Although the incidence of non-tuberculous mycobacterial pulmonary disease
(NTM-PD) is increasing annually, it is easily misdiagnosed as pulmonary tuberculosis (PTB) …

Integrating systemic immune-inflammation index, fibrinogen, and T-SPOT. TB for precision distinction of active pulmonary tuberculosis in the era of mycobacterial …

Z Yu, Z Shang, Q Huang, F Wen, S Patil - Frontiers in Microbiology, 2024 - frontiersin.org
Background The clinical challenge of differentiating suspected tuberculosis with positive T-
SPOT. TB results persist. This study aims to investigate the utility of the Systemic Immune …

Low concordance between QIAreach QuantiFERON-TB, a novel interferon-gamma release assay, and QuantiFERON-TB Gold Plus, in a population-based survey in …

HM Rickman, MD Phiri, H Mbale… - Journal of Clinical …, 2024 - journals.asm.org
Urgent improvements in the diagnosis and management of Mycobacterium tuberculosis
infection are required to reach End TB goals. Conventional interferon-gamma release …

[HTML][HTML] Quantum Dot-Based Nanosensors for In Vitro Detection of Mycobacterium tuberculosis

VV Nikolaev, TB Lepekhina, AS Alliluev, E Bidram… - Nanomaterials, 2024 - mdpi.com
Despite the existing effective treatment methods, tuberculosis (TB) is the second most
deadly infectious disease, its carriers in the latent and active phases accounting for more …

Combining SARS‐CoV‐2 interferon‐gamma release assay with humoral response assessment to define immune memory profiles

W Mouton, G Oriol, C Compagnon… - European Journal of …, 2024 - Wiley Online Library
Objectives In the post‐SARS‐CoV‐2 pandemic era,“breakthrough infections” are still
documented, due to variants of concerns (VoCs) emergence and waning humoral immunity …

Performance evaluation of the LIOFeron® TB/LTBI IGRA for screening of paediatric LTBI and tuberculosis

C Della Bella, MA Motisi, E Venturini, S D'Elios… - European Journal of …, 2025 - Springer
Purpose: High-accuracy diagnostic screening tests for Mycobacterium tuberculosis (MTB)
infection are required, primarily to detect patients with latent infections (LTBIs) in order to …