RNA interference
GJ Hannon - nature, 2002 - nature.com
A conserved biological response to double-stranded RNA, known variously as RNA
interference (RNAi) or post-transcriptional gene silencing, mediates resistance to both …
interference (RNAi) or post-transcriptional gene silencing, mediates resistance to both …
Plant retrotransposons
A Kumar, JL Bennetzen - Annual review of genetics, 1999 - annualreviews.org
▪ Abstract Retrotransposons are mobile genetic elements that transpose through reverse
transcription of an RNA intermediate. Retrotransposons are ubiquitous in plants and play a …
transcription of an RNA intermediate. Retrotransposons are ubiquitous in plants and play a …
[HTML][HTML] Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila
Drosophila Piwi-family proteins have been implicated in transposon control. Here, we
examine piwi-interacting RNAs (piRNAs) associated with each Drosophila Piwi protein and …
examine piwi-interacting RNAs (piRNAs) associated with each Drosophila Piwi protein and …
Epigenetics: regulation through repression
AP Wolffe, MA Matzke - science, 1999 - science.org
Epigenetics is the study of heritable changes in gene expression that occur without a
change in DNA sequence. Epigenetic phenomena have major economic and medical …
change in DNA sequence. Epigenetic phenomena have major economic and medical …
On the role of RNA amplification in dsRNA-triggered gene silencing
T Sijen, J Fleenor, F Simmer, KL Thijssen, S Parrish… - Cell, 2001 - cell.com
We have investigated the role of trigger RNA amplification during RNA interference (RNAi)
in Caenorhabditis elegans. Analysis of small interfering RNAs (siRNAs) produced during …
in Caenorhabditis elegans. Analysis of small interfering RNAs (siRNAs) produced during …
Targeted mRNA degradation by double-stranded RNA in vitro
Double-stranded RNA (dsRNA) directs gene-specific, post-transcriptional silencing in many
organisms, including vertebrates, and has provided a new tool for studying gene function …
organisms, including vertebrates, and has provided a new tool for studying gene function …
Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline
Background: The injection of double-stranded RNA (dsRNA) has been shown to induce a
potent sequence-specific inhibition of gene function in diverse invertebrate and vertebrate …
potent sequence-specific inhibition of gene function in diverse invertebrate and vertebrate …
Post-transcriptional gene silencing by double-stranded RNA
Imagine being able to knock out your favourite gene with only a day's work. Not just in one
model system, but in virtually any organism: plants, flies, mice or cultured cells. This sort of …
model system, but in virtually any organism: plants, flies, mice or cultured cells. This sort of …
RNAi and heterochromatin assembly
R Martienssen, D Moazed - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
The involvement of RNA interference (RNAi) in heterochromatin formation has become clear
largely through studies in the fission yeast Schizosaccharomyces pombe and plants like …
largely through studies in the fission yeast Schizosaccharomyces pombe and plants like …
From silencing to gene expression: real-time analysis in single cells
SM Janicki, T Tsukamoto, SE Salghetti, WP Tansey… - Cell, 2004 - cell.com
We have developed an inducible system to visualize gene expression at the levels of DNA,
RNA and protein in living cells. The system is composed of a 200 copy transgene array …
RNA and protein in living cells. The system is composed of a 200 copy transgene array …