Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Motor neuron (MN) diseases, including amyotrophic lateral sclerosis, progressive bulbar
palsy, primary lateral sclerosis and spinal muscular atrophy, cause progressive paralysis …

Neuromuscular junctions (NMJs) ensure communication between motor neurons (MNs) and
muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs …

An aging population leads to increasing demand for sustained quality of life with the aid of
novel implants. Patients expect fast healing and few complications after surgery. Increased …

Compartmentalized microfluidic neural cell culture platforms, which physically separate
axons from the neural soma using a series of microchannels, have been used for studying a …

Highlights•iPSC-derived NMP cells generate self-organized neuromuscular junction
models.•Neuromuscular organoids form functional NMJs supported by terminal Schwann …

Over the past 20 years, the use of pluripotent stem cells to mimic the complexities of the
human neuromuscular junction has received much attention. Deciphering the key …

Recent years have witnessed a spurt of progress in the application of the encoding and
decoding of neural activities to drug screening, diseases diagnosis, and brain–computer …

In the neuromuscular system, signal transmission from motor neurons (MNs) to innervated
muscle fibers is crucial for their synaptic function, viability, and maintenance. In order to …

Aging is associated with the disruption of protein homeostasis and causally contributes to
multiple diseases, including amyotrophic lateral sclerosis (ALS). One strategy for restoring …