The poor water solubility of active pharmaceutical ingredients (APIs) is a major challenge in
the pharmaceutical industry. Co-solvents are sometimes added to enhance drug dissolution …

Solubility is a critical parameter in drug formulation to achieve the desired therapeutical
concentration. Most drugs are weak acids or bases and, therefore, exhibit low solubility and …

Solubility data of naphazoline nitrate in four binary solvents namely “methanol/2-
methoxyethanol/ethylene glycol/N, N-dimethylformamide plus isopropanol” was determined …

To determine parathion in cereals, hydrophilic and hydrophobic deep eutectic solvents
(DESs) were used by digital image colorimetry with smartphones. In the solid-liquid …

This work reports the aqueous solubility of acetaminophen (ACP), a most traditionally used
analgesics and antipyretic drug, in betaine/propylene glycol deep eutectic solvent (Bet/PG …

The present study is aimed at solving the problem of poor solubility of the antituberculosis
drug thioacetazone (TAZ), the use of which, despite its effectiveness, is limited by toxicity …

As an antihypertensive drug, methyldopa (MD) plays a vital role in for clinical treatment of
moderate, severe or malignant hypertension, especially for secondary hypertension …

The solubility of sulfaguanidine (SG) in water, methanol, ethanol, n-propanol, isopropanol, n-
butanol and binary solvent systems (water+ methanol/n-propanol) was determined by the …

This research aimed to explore the utility of natural deep eutectic solvents (NADES) as the
co-solvents for slightly water-soluble metronidazole (MNZ). After testing 70 wt%(percentage …

New environmentally friendly extraction methods and solvents such as ultrasound assisted
extraction (UAE) and natural deep eutectic solvents (NADES) are replacing the traditional …