Role of the eye in transmitting human coronavirus: what we know and what we do not know

C Sun, Y Wang, G Liu, Z Liu - Frontiers in public health, 2020 - frontiersin.org
The outbreak of the current 2019 novel coronavirus (2019-nCoV, now named SARS-CoV-2)
infection has become a worldwide health threat. Currently, more information is needed so as …

Mechanistic modeling of SARS‐CoV‐2 and other infectious diseases and the effects of therapeutics

AS Perelson, R Ke - Clinical Pharmacology & Therapeutics, 2021 - Wiley Online Library
Modern viral kinetic modeling and its application to therapeutics is a field that attracted the
attention of the medical, pharmaceutical, and modeling communities during the early days of …

Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening

DB Larremore, B Wilder, E Lester, S Shehata… - Science …, 2021 - science.org
The COVID-19 pandemic has created a public health crisis. Because SARS-CoV-2 can
spread from individuals with presymptomatic, symptomatic, and asymptomatic infections, the …

[HTML][HTML] Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance

DB Larremore, B Wilder, E Lester, S Shehata, JM Burke… - MedRxiv, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic has created a public health crisis. Because SARS-CoV-2 can
spread from individuals with pre-symptomatic, symptomatic, and asymptomatic infections …

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS …

KS Kim, K Ejima, S Iwanami, Y Fujita, H Ohashi… - PLoS …, 2021 - journals.plos.org
The scientific community is focused on developing antiviral therapies to mitigate the impacts
of the ongoing novel coronavirus disease 2019 (COVID-19) outbreak. This will be facilitated …

[HTML][HTML] A review of mathematical model-based scenario analysis and interventions for COVID-19

R Padmanabhan, HS Abed, N Meskin, T Khattab… - Computer Methods and …, 2021 - Elsevier
Mathematical model-based analysis has proven its potential as a critical tool in the battle
against COVID-19 by enabling better understanding of the disease transmission dynamics …

SARS‐CoV‐2 coinfections: Could influenza and the common cold be beneficial?

L Pinky, HM Dobrovolny - Journal of Medical Virology, 2020 - Wiley Online Library
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
rapidly spread around the world, causing serious illness and death and creating a heavy …

Modeling within-host SARS-CoV-2 infection dynamics and potential treatments

M Sadria, AT Layton - Viruses, 2021 - mdpi.com
The goal of this study was to develop a mathematical model to simulate the actions of drugs
that target SARS-CoV-2 virus infection. To accomplish that goal, we have developed a …

Digital twin for drug discovery and development—the virtual liver

K Subramanian - Journal of the Indian Institute of Science, 2020 - Springer
Digital twins are defined as digital replicas of processes, systems or devices developed to
foster deeper understanding and prediction. While the concept of digital twins has largely …

Merits and limitations of mathematical modeling and computational simulations in mitigation of COVID-19 pandemic: A comprehensive review

A Afzal, CA Saleel, S Bhattacharyya, N Satish… - … Methods in Engineering, 2022 - Springer
Mathematical models have assisted in describing the transmission and propagation
dynamics of various viral diseases like MERS, measles, SARS, and Influenza; while the …