Clock genes, inflammation and the immune system—implications for diabetes, obesity and neurodegenerative diseases

E Vieira, GG Mirizio, GR Barin, RV De Andrade… - International Journal of …, 2020 - mdpi.com
Inflammation is a common feature of several diseases, including obesity, diabetes and
neurodegenerative disorders. Circadian clock genes are expressed and oscillate in many …

Circadian and immunity cycle talk in cancer destination: from biological aspects to in silico analysis

M Mirian, A Hariri, M Yadollahi, M Kohandel - Cancers, 2022 - mdpi.com
Simple Summary The circadian cycle is a natural cycle of the body repeated every 24 h,
based on a day and night rhythm, and it affects many body processes. The present article …

Lizhong Decoction (理中汤) Ameliorates Ulcerative Colitis in Mice via Regulation of Plasma and Urine Metabolic Profiling

L Wang, J Tao, Y Chen, Y Shen, S Jiang - Chinese journal of integrative …, 2021 - Springer
Objective To elucidate the mechanism of Lizhong Decoction (LZD, 理中汤) in treating
dextran sodium sulfate (DSS)-induced colitis in mice based on metabonomics. Methods …

[HTML][HTML] Npy transcription is regulated by noncanonical STAT3 signaling in hypothalamic neurons: Implication with lipotoxicity and obesity

W He, N Loganathan, A Tran, DD Belsham - Molecular and Cellular …, 2024 - Elsevier
Neuropeptide Y (Npy) is an abundant neuropeptide expressed in the central and peripheral
nervous systems. NPY-secreting neurons in the hypothalamic arcuate nucleus regulate …

The circadian machinery links metabolic disorders and depression: a review of pathways, proteins and potential pharmacological interventions

E Pitsillou, J Liang, A Hung, TC Karagiannis - Life Sciences, 2021 - Elsevier
Circadian rhythms are responsible for regulating a number of physiological processes. The
central oscillator is located within the suprachiasmatic nucleus (SCN) of the hypothalamus …

Mucosal circadian rhythm pathway genes altered by aging and periodontitis

JL Ebersole, OA Gonzalez - Plos one, 2022 - journals.plos.org
As circadian processes can impact the immune system and are affected by infections and
inflammation, this study examined the expression of circadian rhythm genes in periodontitis …

Electrochemical nanobiosensors as point‐of‐care testing solution to cytokines measurement limitations

DJ Pérez, EB Patiño, J Orozco - Electroanalysis, 2022 - Wiley Online Library
Most cytokines are present at reduced amounts in body fluids due to their biological features
of production, release, and action mechanisms. The required time between sampling and …

The role of nonesterified fatty acids in cancer biology: Focus on tryptophan and related metabolism

AAB Badawy - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2024 - Elsevier
Plasma nonesterified fatty acids (NEFA) are elevated in cancer, because of decreased
albumin levels and of fatty acid oxidation, and increased fatty acid synthesis and lipolysis …

12-week melatonin administration had no effect on diabetes risk markers and fat intake in overweight women night workers

CAR de Sousa, LF Nogueira, J Cipolla-Neto… - Frontiers in …, 2024 - frontiersin.org
Introduction Interactions between circadian clocks and key mediators of chronic low-grade
inflammation associated with fat consumption may be important in maintaining metabolic …

Dietary factors in circadian rhythm modulation and their impact on metabolic diseases: a state of the science review

M Dalvi, S Medithi - Biological Rhythm Research, 2024 - Taylor & Francis
Biological functions of living things are regulated by the circadian rhythm, a 24-hour cycle.
Master clock in the hypothalamus is dependent on light-dark signals, while peripheral clock …