Pelvic organ prolapse is a vaginal protrusion of female pelvic organs. It has high prevalence
worldwide and represents a great burden to the economy. The pathophysiology of pelvic …

Pelvic organ prolapse (POP) and urinary incontinence (UI) are common disorders that
significantly impact women's quality of life. Studies have demonstrated that cytokines …

The aim of the present study was to investigate the ultrastructure and content of collagen in
uterosacral ligaments and paraurethral tissues in patients with pelvic organ prolapse (POP) …

Aim: The molecular etiology of pelvic organ prolapse (POP) is complex and not well
understood. We compared the expression/activity of extracellular matrix (ECM)-processing …

Gynaecologists are becoming increasingly aware that women with a family history of
prolapse are at an increased risk of prolapse refractory to treatment. In the past five years …

Pelvic organ prolapse (POP) is characterized by weakening of the connective tissues and
loss of support for the pelvic organs. Collagen is the predominant, load-bearing protein …

Introduction and hypothesis The objective was to explore the current practice of using
animal models for female pelvic floor dysfunction (PFD). Methods By applying PFD and …

Pelvic organ prolapse (POP) is a common gynecological benign disease occurring in middle‑
aged and elderly females. Its incidence increases every year. To date, the majority of studies …

Abstract Purpose To investigate the Homeobox genes HOXA-10 and HOXA-11 mediated
endometrial molecular defects during implantation window in endometriosis-associated …

Background: This study tested a hypothesis that primary human vaginal cells derived from
tissue of premenopausal women with severe pelvic organ prolapse (POP-HVCs) would …