[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

A comprehensive review on nutraceuticals: therapy support and formulation challenges

V Puri, M Nagpal, I Singh, M Singh, GA Dhingra… - Nutrients, 2022 - mdpi.com
Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that
are biologically active and possess capability for maintaining optimal health and benefits …

Multi-site isomerization of synergistically regulated stimuli-responsive AIE materials toward multi-level decryption

W Zhong, J Zhang, Y Lin, S Li, Y Yang, WJ Wang… - Chemical …, 2024 - pubs.rsc.org
Stimuli-responsive aggregation-induced emission (AIE) materials are highly sensitive and
rapidly responsive to external signals, making them ideal solid materials for anti …

Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs

P Mohite, S Singh, A Pawar, A Sangale… - Frontiers in Drug …, 2023 - frontiersin.org
Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical
development, which is linked to their limited oral bioavailability and therapeutic efficacy. To …

Development of polyvinylpyrrolidone-based nanomaterials for biosensors applications: a review

M Pourmadadi, A Shamsabadipour, A Aslani… - Inorganic Chemistry …, 2023 - Elsevier
A biosensor is an analytical tool applied for biomarkers' specific and sensitive detection.
Using biosensors in clinical settings leads to trustworthy, precise, and quantitative …

[HTML][HTML] Self-emulsifying drug delivery systems (SEDDS) disrupt the gut microbiota and trigger an intestinal inflammatory response in rats

S Subramaniam, A Elz, A Wignall, S Kamath… - International Journal of …, 2023 - Elsevier
Self-emulsifying drug delivery systems (ie SEDDS, SMEDDS and SNEDDS) are widely
employed as solubility and bioavailability enhancing formulation strategies for poorly water …

Fish oil-based microemulsion can efficiently deliver oral peptide blocking PD-1/PD-L1 and simultaneously induce ferroptosis for cancer immunotherapy

X Yang, W Li, S Li, S Chen, Z Hu, Z He, X Zhu… - Journal of Controlled …, 2024 - Elsevier
Peptide immune checkpoint inhibitors in cancer immunotherapy have attracted great
attention recently, but oral delivery of these peptides remains a huge challenge due to the …

Self-emulsifying drug delivery systems: a novel approach to deliver drugs

A Salawi - Drug Delivery, 2022 - Taylor & Francis
Self-emulsifying drug delivery systems (SEDDS) are a proven method for poorly soluble
substances works by increasing the solubility and bioavailability. SEDDS and isotropic …

Twin screw melt granulation: a single step approach for developing self-emulsifying drug delivery system for lipophilic drugs

D Nyavanandi, P Mandati, S Narala, A Alzahrani… - Pharmaceutics, 2023 - mdpi.com
The current research aims to improve the solubility of the poorly soluble drug, ie, ibuprofen,
by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt …

Recent advances in targeted nanocarriers for the management of Triple negative breast Cancer

R Pradhan, A Dey, R Taliyan, A Puri, S Kharavtekar… - Pharmaceutics, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is a life-threatening form of breast cancer which has
been found to account for 15% of all the subtypes of breast cancer. Currently available …