Artificial intelligence in neurology: opportunities, challenges, and policy implications

S Voigtlaender, J Pawelczyk, M Geiger, EJ Vaios… - Journal of …, 2024 - Springer
Neurological conditions are the leading cause of disability and mortality combined,
demanding innovative, scalable, and sustainable solutions. Brain health has become a …

[HTML][HTML] Biomarker-Based Precision Therapy for Alzheimer's Disease: Multidimensional Evidence Leading a New Breakthrough in Personalized Medicine

A Bougea, P Gourzis - Journal of Clinical Medicine, 2024 - mdpi.com
(1) Background: Alzheimer's disease (AD) is a worldwide neurodegenerative disorder
characterized by the buildup of abnormal proteins in the central nervous system and …

Enhancing Equity in Genomics: Incorporating Measures of Structural Racism, Discrimination, and Social Determinants of Health

RM Rajagopalan, M D'Antonio… - Hastings Center …, 2024 - Wiley Online Library
The everyday harms of structural racism and discrimination, perpetuated through institutions,
laws, policies, and practices, constitute social determinants of health, but measures that …

Optimizing clinico-genomic disease prediction across ancestries: a machine learning strategy with Pareto improvement

Y Gao, Y Cui - Genome Medicine, 2024 - Springer
Background Accurate prediction of an individual's predisposition to diseases is vital for
preventive medicine and early intervention. Various statistical and machine learning models …

Stacked neural network for predicting polygenic risk score

S Kim, JH Kang, MJ Cheon, DJ Kim, BC Lee - Scientific Reports, 2024 - nature.com
In recent years, the utility of polygenic risk scores (PRS) in forecasting disease susceptibility
from genome-wide association studies (GWAS) results has been widely recognised. Yet …

The application of artificial intelligence in diagnosis of Alzheimer's disease: a bibliometric analysis

X An, J He, B Bi, G Wu, J Xu, W Yu, Z Ren - Frontiers in Neurology, 2024 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that severely impacts cognitive
function, posing significant physical and psychological burdens on patients and substantial …

[HTML][HTML] 人工智能在阿尔茨海默病临床诊疗中的研究热点及前沿趋势分析

余如霞, 姜婧, 王湫澄, 王越, 赵小月 - 中国全科医学, 2024 - chinagp.net
背景目前, 人工智能应用于阿尔茨海默病(AD) 领域的研究论文数量增幅较大,
明确该领域最新研究热点和未来发展趋势十分重要. 目的通过应用文献计量学分析 …

Polygenic risk for Alzheimer's disease is associated with neuroaxonal damage before onset of clinical symptoms

SM Kagerer, S Awasthi, S Ripke… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Establishing valid diagnostic strategies is a precondition for successful
therapeutic intervention in Alzheimer's disease (AD). METHODS One hundred forty‐four …

Machine Learning to Advance Human Genome-Wide Association Studies

RE Sigala, V Lagou, A Shmeliov, S Atito, S Kouchaki… - Genes, 2023 - mdpi.com
Machine learning, including deep learning, reinforcement learning, and generative artificial
intelligence are revolutionising every area of our lives when data are made available. With …

Genetics and biomarkers of Alzheimer's disease in Asian populations

X Zhou, KY Mok, AKY Fu - Frontiers in Neuroscience, 2024 - frontiersin.org
Alzheimer's disease (AD) is a significant global health concern, with its impact amplified by
the aging population. Researchers have been working to unravel the intricate mechanisms …