Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

Sleep homeostasis and circadian function are important maintaining factors for optimal
health and well-being. Conversely, sleep and circadian disruptions are implicated in a …

Cigarette smoking is often initiated during adolescence and an earlier age of onset is
associated with worse health outcomes later in life. Paradoxically, the transition towards …

Induction of neuroimmune genes by binge drinking increases neuronal excitability and
oxidative stress, contributing to the neurobiology of alcohol dependence and causing …

The adolescent transition is associated with increases in reward-and sensation-seeking,
peer-directed social interactions, and risk-taking, with exploratory use of alcohol and other …

Substance use and abuse begin during adolescence. Male and female adolescent humans
initiate use at comparable rates, but males increase use faster. In adulthood, more men than …

Alcohol use is typically initiated during adolescence, which, along with young adulthood, is a
vulnerable period for the onset of high-risk drinking and alcohol abuse. Given across …

The light/dark (LD) test is a commonly used rodent test of unconditioned anxiety-like
behavior that is based on an approach/avoidance conflict between the drive to explore novel …

Alcohol-induced brain damage likely contributes to the dysfunctional poor decisions
associated with alcohol dependence. Human alcoholics have a global loss of brain volume …

Adolescence is an evolutionarily conserved developmental period, with neural circuits and
behaviors contributing to the detection, procurement, and receipt of rewards bearing …