CC chemokines in a tumor: a review of pro-cancer and anti-cancer properties of the ligands of receptors CCR1, CCR2, CCR3, and CCR4
J Korbecki, K Kojder, D Simińska… - International journal of …, 2020 - mdpi.com
CC chemokines, a subfamily of 27 chemotactic cytokines, are a component of intercellular
communication, which is crucial for the functioning of the tumor microenvironment. Although …
communication, which is crucial for the functioning of the tumor microenvironment. Although …
The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases
Chemokines are small proteins that control several tissue functions, including cell
recruitment and activation under homeostatic and inflammatory conditions. CXCL8 …
recruitment and activation under homeostatic and inflammatory conditions. CXCL8 …
[HTML][HTML] IL-6, IL-8 and TNF-α levels correlate with disease stage in breast cancer patients
Y Ma, Y Ren, ZJ Dai, CJ Wu, YH Ji… - Advances in Clinical and …, 2017 - advances.umw.edu.pl
Background. Breast cancer is the most common cancer in Chinese women. Inflammation
contributes to tumor progression and can be induced by excessive production of pro …
contributes to tumor progression and can be induced by excessive production of pro …
The breast tumor microenvironment: role in cancer development, progression and response to therapy
Introduction: Numerous clinical and pre-clinical studies have provided ample evidence
supporting that the tumor microenvironment plays a significant role during breast cancer …
supporting that the tumor microenvironment plays a significant role during breast cancer …
Extracellular matrix modulates angiogenesis in physiological and pathological conditions
A Neve, FP Cantatore, N Maruotti… - BioMed research …, 2014 - Wiley Online Library
Angiogenesis is a multistep process driven by a wide range of positive and negative
regulatory factors. Extracellular matrix (ECM) plays a crucial role in the regulation of this …
regulatory factors. Extracellular matrix (ECM) plays a crucial role in the regulation of this …
Inflammatory breast cancer promotes development of M2 tumor-associated macrophages and cancer mesenchymal cells through a complex chemokine network
A Valeta-Magara, A Gadi, V Volta, B Walters, R Arju… - Cancer research, 2019 - AACR
Inflammatory breast cancer (IBC) is a highly aggressive form of breast cancer that displays
profound cancer stem cell (CSC) and mesenchymal features that promote rapid metastasis …
profound cancer stem cell (CSC) and mesenchymal features that promote rapid metastasis …
Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes
Today obesity and type 2 diabetes (T2D) have both reached epidemic proportions.
However, our current understanding of the primary mechanisms leading to these diseases is …
However, our current understanding of the primary mechanisms leading to these diseases is …
High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
Abstract Inflammatory Breast Cancer (IBC) is a highly aggressive malignancy with distinct
clinical and histopathological features whose molecular basis is unresolved. Here we …
clinical and histopathological features whose molecular basis is unresolved. Here we …
Undifferentiated carcinoma with osteoclastic giant cells of the pancreas: clinicopathologic analysis of 38 cases highlights a more protracted clinical course than …
Undifferentiated carcinomas with osteoclastic giant cells of the pancreas (OGC) are rare
tumors. The current impression in the literature is that they are highly aggressive tumors …
tumors. The current impression in the literature is that they are highly aggressive tumors …
Matrix stiffness and tumor-associated macrophages modulate epithelial to mesenchymal transition of human adenocarcinoma cells
The tumor microenvironment (TME) is gaining increasing attention in oncology, as it is
recognized to be functionally important during tumor development and progression. Tumors …
recognized to be functionally important during tumor development and progression. Tumors …