Modeling composite assessment data using item response theory
S Ueckert - CPT: Pharmacometrics & Systems Pharmacology, 2018 - Wiley Online Library
Composite assessments aim to combine different aspects of a disease in a single score and
are utilized in a variety of therapeutic areas. The data arising from these evaluations are …
are utilized in a variety of therapeutic areas. The data arising from these evaluations are …
Supervised multidimensional item response theory modeling of pediatric iatrogenic withdrawal symptoms
SC Goulooze, E Ista, M van Dijk… - CPT …, 2019 - Wiley Online Library
Item‐level data from composite scales can be analyzed with pharmacometric item response
theory (IRT) models to improve the quantification of disease severity compared with the use …
theory (IRT) models to improve the quantification of disease severity compared with the use …
[PDF][PDF] Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics: Tools of the trade
SC Goulooze - 2020 - scholarlypublications …
Objectives: Characterizing the risk of iatrogenic withdrawal syndrome (IWS) over time and
exploring optimal weaning strategies in model-based simulations Design: Population …
exploring optimal weaning strategies in model-based simulations Design: Population …
Differentiation and prognosis of healthy subjects, swedds and parkinson's patients using a multi-dimensional item response theory model
Background: Previous investigations showed the merit of Item Response Theory (IRT)
models for the differentiation between Parkinson's disease (PD) patients and SWEDDs [1, 2] …
models for the differentiation between Parkinson's disease (PD) patients and SWEDDs [1, 2] …
[引用][C] Non-motor symptoms (nms) improvement is correlated with baseline nms burden and improved quality of life (QoL) in levodopa-carbidopa intestinal gel (LCIG) …
KR Chaudhuri, W Poewe, L Bergmann… - Journal of the …, 2017 - jns-journal.com
Background: LCIG, delivered via percutaneous gastrojejunostomy, significantly improved
NMS and QoL in the GLORIA registry (IRB-approved) at 24-months (M). Objective: A post …
NMS and QoL in the GLORIA registry (IRB-approved) at 24-months (M). Objective: A post …
[引用][C] Effects of repetetive transcranial magnetic stimulation at three cortical sites in parkinson's disease: a randomized study
P Bhat, V Goyal, AK Srivastava… - Journal of the …, 2017 - jns-journal.com
Background: Parkinson's disease (PD) is a progressive neurological disorder characterized
by a broad spectrum of motor and non-motor symptoms. Objective: To investigate the …
by a broad spectrum of motor and non-motor symptoms. Objective: To investigate the …