Most bacterial pathogens have the remarkable ability to flourish in the external environment and in specialized host niches. This ability requires their metabolism, physiology, and …
In many γ‐proteobacteria, the conserved GacS/GacA (BarA/UvrY) two‐component system positively controls the expression of one to five genes specifying small RNAs (sRNAs) that …
A Brencic, KA McFarland, HR McManus… - Molecular …, 2009 - Wiley Online Library
We report here the results of an analysis of the regulatory range of the GacS/GacA two‐ component system in Pseudomonas aeruginosa. Using microarrays, we identified a large …
P Babitzke, T Romeo - Current opinion in microbiology, 2007 - Elsevier
Noncoding regulatory RNA molecules, also known as small RNAs, participate in several bacterial regulatory networks. The central component of the carbon storage regulator (Csr) …
Originally described as a repressor of gene expression in the stationary phase of growth, CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation …
E Van Assche, S Van Puyvelde… - Frontiers in …, 2015 - frontiersin.org
Post-transcriptional regulation is a very important mechanism to control gene expression in changing environments. In the past decade, a lot of interest has been directed toward the …
G Oliva, T Sahr, C Buchrieser - Frontiers in cellular and infection …, 2018 - frontiersin.org
Legionella pneumophila is a gram-negative bacterium that inhabits freshwater ecosystems, where it is present in biofilm or as planktonic form. L. pneumophila is mainly found …
J Timmermans, L Van Melderen - Cellular and molecular life sciences, 2010 - Springer
Global regulation allows bacteria to rapidly modulate the expression of a large variety of unrelated genes in response to environmental changes. Global regulators act at different …
Infectious diseases are a leading cause of mortality worldwide. A major challenge in achieving their eradication is a better understanding of bacterial pathogenesis processes …