MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …

Since their discovery 20 years ago, miRNAs have attracted much attention from all areas of
biology. These short (∼ 22 nt) non-coding RNA molecules are highly conserved in evolution …

Background Liver cancer ranks the top four malignant cancer type worldwide, which needs
effective and safe treatment. Ferroptosis is a novel form of regulated cell death driven by iron …

MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

Protein synthesis is principally regulated at the initiation stage (rather than during elongation
or termination), allowing rapid, reversible and spatial control of gene expression. Progress …

MicroRNAs (miRNAs) are small noncoding RNAs that extensively regulate gene expression
in animals, plants, and protozoa. miRNAs function posttranscriptionally by usually base …

Since the discovery in 1993 of the first small silencing RNA, a dizzying number of small RNA
classes have been identified, including microRNAs (miRNAs), small interfering RNAs …

Recently, the transcription factor encoded by tumor suppressor gene p53 was shown to
regulate the expression of microRNAs. The most significant induction by p53 was observed …

MicroRNAs (miRNAs) control gene expression through both translational repression and
degradation of target messenger RNAs (mRNAs). However, the interplay between these …

MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression in most
biological processes. They act by guiding the RNAi-induced silencing complex (RISC) to …