Background Several studies have reported an association between maternal hypertensive
disorders and hypospadias in offspring; however there is still debate on the role of maternal …

Hypospadias is a common birth defect where the urethral opening forms on the ventral side
of the penis. We performed integrative methylomic, genomic, and transcriptomic analyses to …

Background Hypospadias is one of the most common male congenital malformations
worldwide. It is characterised by the abnormal positioning of the opening of urethra, and may …

Introduction Previous studies have suggested that hypertensive disorders of pregnancy
increase risk of hypospadias, but so far none have focused on the influence of maternal …

Background Hypospadias is more common among male infants with growth restriction,
defined as a birth weight less than the 10th centile, than in infants with a normal birth weight …

Background: Although congenital abnormalities in the male reproductive tract are common,
their causes remain poorly understood. We studied associations between hypertensive …

Objective To determine the prevalence of genetic and endocrine abnormalities and to
assess fetal, neonatal and surgical outcomes in cases of hypospadias associated with fetal …

尿道下裂居于常见的男性先天性生殖器畸形第2 位, 近20~ 40 年, 全世界范围发病率报道不一,
其病因及发病机制尚不明确, 且存在地理, 区域及种族差异. 目前绝大多数相关研究数据来自国外 …

Background Inconsistent relationships have been shown between cigarette smoking and
hypospadias in offspring. The purpose of this study was to summarize epidemiological …

Background Hypospadias is a frequently occurring congenital anomaly in male infants, in
which the opening of the urethra is located along the ventral side of the penis. Although …