Renal denervation in the management of hypertension in adults. A clinical consensus statement of the ESC Council on Hypertension and the European Association of …

E Barbato, M Azizi, RE Schmieder… - European Heart …, 2023 - academic.oup.com
Since the publication of the 2018 European Society of Cardiology/European Society of
Hypertension (ESC/ESH) Guidelines for the Management of Arterial Hypertension, several …

Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial

F Mahfoud, DE Kandzari, K Kario, RR Townsend… - The Lancet, 2022 - thelancet.com
Background Renal denervation has been shown to lower blood pressure in the presence of
antihypertensive medications; however, long-term safety and efficacy data from randomised …

Endovascular ultrasound renal denervation to treat hypertension: the RADIANCE II randomized clinical trial

M Azizi, M Saxena, Y Wang, JS Jenkins, C Devireddy… - Jama, 2023 - jamanetwork.com
Importance Two initial sham-controlled trials demonstrated that ultrasound renal denervation
decreases blood pressure (BP) in patients with mild to moderate hypertension and …

Effects of renal denervation on sympathetic nerve traffic and correlates in drug-resistant and uncontrolled hypertension: a systematic review and meta-analysis

A Biffi, R Dell'Oro, F Quarti-Trevano, C Cuspidi… - …, 2023 - Am Heart Assoc
Background: Whether and to what extent the reported blood pressure (BP) lowering effects
of renal denervation (RDN) are associated with a central sympathoinhibition is controversial …

Patient-level pooled analysis of ultrasound renal denervation in the sham-controlled RADIANCE II, RADIANCE-HTN SOLO, and RADIANCE-HTN TRIO trials

AJ Kirtane, ASP Sharp, F Mahfoud, NDL Fisher… - JAMA …, 2023 - jamanetwork.com
Importance Ultrasound renal denervation (uRDN) was shown to lower blood pressure (BP)
in patients with uncontrolled hypertension (HTN). Establishing the magnitude and …

Effects of renal denervation vs sham in resistant hypertension after medication escalation: prespecified analysis at 6 months of the RADIANCE-HTN TRIO randomized …

M Azizi, F Mahfoud, MA Weber, ASP Sharp… - JAMA …, 2022 - jamanetwork.com
Importance Although early trials of endovascular renal denervation (RDN) for patients with
resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was …

Patient-level pooled analysis of endovascular ultrasound renal denervation or a sham procedure 6 months after medication escalation: the RADIANCE clinical trial …

M Azizi, ASP Sharp, NDL Fisher, MA Weber, MD Lobo… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The randomized, sham-controlled RADIANCE-HTN (A Study of the Recor
Medical Paradise System in Clinical Hypertension) SOLO, RADIANCE-HTN TRIO, and …

Renal denervation in patients with chronic kidney disease: current evidence and future perspectives

RE Schmieder - Nephrology Dialysis Transplantation, 2023 - academic.oup.com
Supported by several high-quality randomized controlled trials and registry analyses,
catheter-based renal denervation is becoming an important adjunctive treatment modality for …

Efficacy and safety of catheter-based radiofrequency renal denervation in Chinese patients with uncontrolled hypertension: the randomized, sham-controlled, multi …

X Jiang, F Mahfoud, W Li, H Dong, J Yu, S Yu, X Chen… - Circulation, 2024 - ahajournals.org
BACKGROUND: Renal denervation (RDN) can lower blood pressure (BP) in patients with
hypertension in both the presence and absence of medication. This is a sham-controlled trial …

Effects of catheter-based renal denervation in hypertension: a systematic review and meta-analysis

D Vukadinović, L Lauder, DE Kandzari, DL Bhatt… - Circulation, 2024 - ahajournals.org
BACKGROUND: Several sham-controlled trials have investigated the efficacy and safety of
catheter-based renal denervation (RDN) with mixed outcomes. We aimed to perform a …