Development of potential cathepsin B inhibitors: Synthesis of new bithiazole derivatives, in vitro studies supported with theoretical docking studies
S Yadav, C Vashisth, V Chaudhri, K Singh… - International Journal of …, 2024 - Elsevier
Cysteine cathepsins play a crucial role in cancer, inflammation, and the regulation of
degenerative processes such as apoptosis, making them significant targets in drug …
degenerative processes such as apoptosis, making them significant targets in drug …
Chalcones as potential pepsin inhibitors: Synthesis, characterization, DFT and molecular docking studies
Pepsin, a unique protease activity at acidic environment in the stomach, can cause chronic
inflammation in surrounding tissues after becoming hyperactive lead to enlarged tonsils …
inflammation in surrounding tissues after becoming hyperactive lead to enlarged tonsils …
Cinnamaldehyde-based hydrazone schiff bases as inhibitors of pepsin and trypsin: A comparative study
Selective targeting by a therapeutic agent is of significant importance in the development of
a medicinally important compound. In the present work, we report preferential inhibition of …
a medicinally important compound. In the present work, we report preferential inhibition of …
Innovative Pyrazole Hybrids: A New Era in Drug Discovery and Synthesis
Heterocyclic compounds that include nitrogen and their derivatives have long been
regarded as excellent sources of medicinal substances. Pyrazole is a compound with two …
regarded as excellent sources of medicinal substances. Pyrazole is a compound with two …