A Comprehensive Review of The Molecular Dynamic Study Of Chalcones, Coumarins and Chromones as Selective MAO‐B Inhibitors [2015‐Till Date]
R Rachel Thomas, N Chandran… - …, 2024 - Wiley Online Library
Molecular dynamics (MD) simulation is an in silico method used in the biomolecular level of
research to study how the protein interacts with the target with time. It provides a detailed …
research to study how the protein interacts with the target with time. It provides a detailed …
Synthesis, In-Vitro, In-Vivo screening, and molecular docking of disubstituted aminothiazole derivatives and their selenium nanoparticles as potential antiparkinson …
LO El-Halaby, NFA El-Magd, SJ Almehmadi… - Journal of Molecular …, 2024 - Elsevier
Neurological illnesses are among the leading causes of mortality across the world. In the
present work, the synthesis of a new series of substituted aminothiazole derivatives (3a-e) …
present work, the synthesis of a new series of substituted aminothiazole derivatives (3a-e) …
α-Silyl amines as electron donors: application in synthetic organic chemistry
NF Lazareva, IM Lazarev - Russian Chemical Bulletin, 2024 - Springer
Abstract α-Silyl amines are unique organosilicon compounds containing a geminal NCH2Si
fragment. The introduction of a triorganylsilyl group at α-position to the nitrogen atom …
fragment. The introduction of a triorganylsilyl group at α-position to the nitrogen atom …
Elucidating the monoamine oxidase B inhibitory effect of kaurene diterpenoids from Xylopia aethiopica: An in silico approach
FG Famuyiwa, RB Patil, SO Famuyiwa, UI Olayemi… - PloS one, 2024 - journals.plos.org
Parkinson disease is a neurogenerative disease common in adults and results in different
kinds of memory dysfuntions. This study evaluated the monoamine oxidase B (MAO-B) …
kinds of memory dysfuntions. This study evaluated the monoamine oxidase B (MAO-B) …
Effect of Hydroxytyrosol Derivatives of Donepezil on the Activity of Enzymes Involved in Neurodegenerative Diseases and Oxidative Damage
Monoamine oxidase and xanthine oxidase inhibitors represent useful multi-target drugs for
the prevention, attenuation, and treatment of oxidative damage and neurodegenerative …
the prevention, attenuation, and treatment of oxidative damage and neurodegenerative …
Development of morpholine ring-bearing halogenated α, β-unsaturated ketones as selective monoamine oxidase-B inhibitors
J Lee, SK Parmbil, NK Pandit, S Kumar, A Syed… - Applied Biological …, 2024 - Springer
Nine morpholine-derived halogenated chalcone derivatives (MHC1-MHC9) were
synthesized, and their inhibitory activity against monoamine oxidase (MAO) was evaluated …
synthesized, and their inhibitory activity against monoamine oxidase (MAO) was evaluated …
Cheminformatics approach for identification of N-HyMenatPimeMelly as a novel potential ligand against RAS and renal chloride channel
Some angiotensin receptor (AR) blockers interfere with the renal chloride channel (ClC-K),
which plays an important role in urine concentration. Identifying ligands targeting this …
which plays an important role in urine concentration. Identifying ligands targeting this …
Synthesis, Biological Evaluation, Molecular Docking and ADME Studies of Novel Pyrrole-Based Schiff Bases as Dual Acting MAO/AChE Inhibitors
Considering the complex pathogenesis of Alzheimer's disease (AD), the multitarget ligand
strategy is expected to provide superior effects for the treatment of the neurological disease …
strategy is expected to provide superior effects for the treatment of the neurological disease …
In silico Screening of Monamine Oxidase B Inhibitors for the Treatment of Central Nervous System Disorders
ALP Costa, HB Lima, ACJ Silva, GS Oliveira… - Journal of the Brazilian …, 2024 - SciELO Brasil
Worldwide, millions of people suffer from neurological and psychiatric conditions, such as
schizophrenia, depression, and neurodegenerative diseases. These conditions are often …
schizophrenia, depression, and neurodegenerative diseases. These conditions are often …
Investigating In silico and In vitro Therapeutic Potential of Diosmetin as the Anti-Parkinson Agent
KK Varshney, JK Gupta, R Srivastava - Protein & Peptide Letters, 2024 - benthamdirect.com
Aim This study aimed to investigate how diosmetin interacts with seven target receptors
associated with oxidative stress (OS) and validate its antioxidant properties for the potential …
associated with oxidative stress (OS) and validate its antioxidant properties for the potential …