SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of
the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion …

RNA aptamers and RNA aptamer-based devices can be genetically encoded and
expressed in cells to probe and manipulate cellular function. However, their usefulness in …

The discovery of discontiguous tRNA genes triggered studies dissecting the process of tRNA
splicing. As a result, we have gained detailed mechanistic knowledge on enzymatic removal …

Leading experts from all over the world present an overview of the use of enzymes in
industry for:-the production of bulk products, such as glucose, or fructose-food processing …

In clinical diagnostics, as well as food and environmental safety practices, biosensors are
powerful tools for monitoring biological or biochemical processes. Two-dimensional (2D) …

Classical approaches to determine structures of noncoding RNA (ncRNA) probed only one
RNA at a time with enzymes and chemicals, using gel electrophoresis to identify reactive …

Many viruses and certain cellular mRNAs initiate protein synthesis from a highly structured
RNA sequence in the 5′ untranslated region, called the internal ribosome entry site (IRES) …

Publisher Summary This chapter discusses a biosynthetic method for introducing unnatural
amino acids site-specifically into proteins. This method involves the replacement of the …

Mammalian polynucleotide kinases catalyze the 5′-phosphorylation of nucleic acids and
can have associated 3′-phosphatase activity, predictive of an important function in DNA …

Materials and Methods Materials. Blenoxane, a clinical bleomycin sulfate, was generously
supplied by Bristol Laboratories. Thiobarbituric f From the Division of Chemistry and …