Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

Nanopore-based fourth-generation DNA sequencing technology

Y Feng, Y Zhang, C Ying, D Wang… - Genomics, Proteomics …, 2015 - academic.oup.com
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have
the potential to quickly and reliably sequence the entire human genome for less than 1000 …

Discrimination of oligonucleotides of different lengths with a wild-type aerolysin nanopore

C Cao, YL Ying, ZL Hu, DF Liao, H Tian… - Nature …, 2016 - nature.com
Protein nanopores offer an inexpensive, label-free method of analysing single
oligonucleotides. The sensitivity of the approach is largely determined by the characteristics …

[图书][B] Solid-state nanopore sensors for nucleic acid analysis

BM Venkatesan, R Bashir - 2011 - Springer
Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Nanopores: A journey towards DNA sequencing

M Wanunu - Physics of life reviews, 2012 - Elsevier
Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Rapid electronic detection of probe-specific microRNAs using thin nanopore sensors

M Wanunu, T Dadosh, V Ray, J Jin… - Nature …, 2010 - nature.com
Small RNA molecules have an important role in gene regulation and RNA silencing therapy,
but it is challenging to detect these molecules without the use of time-consuming radioactive …

Biomimetic smart nanopores and nanochannels

X Hou, W Guo, L Jiang - Chemical Society Reviews, 2011 - pubs.rsc.org
Nature provides a huge range of biological materials, just as ion channels, with various
smart functions over millions of years of evolution, and which serve as a big source of bio …

Recent progress in solid‐state nanopores

K Lee, KB Park, HJ Kim, JS Yu, H Chae… - Advanced …, 2018 - Wiley Online Library
The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

Nanopore sensors for biomolecular characterization

R Bashir, BM Venkatesan - US Patent 10,175,195, 2019 - Google Patents
Provided herein are methods and devices for characterizing a biomolecule parameter by a
nanopore-containing mem brane, and also methods for making devices that can be used in …