DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Despite rapid advancements in the field of nanotechnology, there is mounting frustration in
the scientific community regarding the translational impact of nanomedicine. Modest …

To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

Drug delivery systems that are externally triggered to release drugs and/or target tissues
hold considerable promise for improving the treatment of many diseases by minimizing …

We rationally engineered an elegant entropy‐driven DNA nanomachine with three‐
dimensional track and applied it for intracellular miRNAs imaging. The proposed …

Activating CD8+ T cells by antigen cross-presentation is remarkably effective at eliminating
tumours. Although this function is traditionally attributed to dendritic cells, tumour-associated …

In this review, we introduce two kinds of bio-related nanoarchitectonics, DNA
nanoarchitectonics and cell-macromolecular nanoarchitectonics, both of which are basically …

Small interfering RNA (siRNA) is an effective therapeutic to regulate the expression of target
genes in vitro and in vivo. Constructing a siRNA delivery system with high serum stability …