Canonical Wnt pathway maintains blood-brain barrier integrity upon ischemic stroke and its activation ameliorates tissue plasminogen activator therapy

N Jean LeBlanc, R Menet, K Picard, G Parent… - Molecular …, 2019 - Springer
Stroke induces blood-brain barrier (BBB) breakdown, which promotes complications like
oedema and hemorrhagic transformation. Administration of recombinant tissue plasminogen …

[HTML][HTML] Inducible prostaglandin E synthase as a pharmacological target for ischemic stroke

L Li, N Yasmen, R Hou, S Yang, JY Lee, J Hao, Y Yu… - …, 2023 - Elsevier
As the inducible terminal enzyme for prostaglandin E2 (PGE 2) synthesis, microsomal PGE
synthase-1 (mPGES-1) contributes to neuroinflammation and secondary brain injury after …

MEPO promotes neurogenesis and angiogenesis but suppresses gliogenesis in mice with acute ischemic stroke

SJ Zhang, RL Wang, HP Zhao, Z Tao, JC Li, F Ju… - European Journal of …, 2019 - Elsevier
Previously study has proved the non-erythropoietic mutant erythropoietin (MEPO) exerted
neuroprotective effects against ischemic cerebral injury, with an efficacy similar to that of wild …

Can pay-for performance incentive levels be determined using a cost-effectiveness framework?

A Pandya, DI Soeteman, A Gupta, H Kamel… - … Quality and Outcomes, 2020 - Am Heart Assoc
Background: Healthcare payers in the United States are increasingly tying provider
payments to quality and value using pay-for-performance policies. Cost-effectiveness …

[HTML][HTML] Multimode computed tomography evaluation of the efficacy and safety of an extended thrombolysis time window (3–9 hours) for acute ischemic stroke: study …

XY Li, W Sun, Y Yang, X Zhang, DM Li… - Asia Pacific Journal of …, 2018 - journals.lww.com
Design: This is a retrospective, single-center, case-analysis clinical trial. Methods: We will
retrospectively collect data from 450 patients with acute ischemic stroke who have …

[PDF][PDF] 药物经济学评价中的风险决策与信息价值分析

石丰豪, 李薇, 韩晟 - 世界临床药物, 2021 - jwph.com.cn
目的探讨药物经济学评价面临的决策风险及量化决策风险的信息价值分析方法.
方法通过实例分析说明药品价格和药品的临床证据对决策风险的影响, 以及如何利用信息价值 …

La voie canonique Wnt est nécessaire pour le maintien de l'intégrité de la barrière hémato-encéphalique après un accident vasculaire cérébral: impacts sur la …

N Jean-Leblanc - 2019 - library-archives.canada.ca
L'accident vasculaire cérébral (AVC) déclenche une perturbation de la barrière hémato-
encéphalique (BHE) et entrave la récupération des tissus en altérant le microenvironnement …

Cost-effectiveness of very brief interventions promoting physical activity: an application of the iterative approach in decision making

V Gc - 2018 - ueaeprints.uea.ac.uk
Economic evaluations are increasingly used in healthcare decision-making. An iterative
approach to economic evaluation has been proposed as good practice in which economic …

[图书][B] Essays in Monetary Economics

C Wang - 2020 - search.proquest.com
Essays in Monetary Economics Page 1 Essays in Monetary Economics by Chenxi Wang A
dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of …

Targeting Neuronal Function to Restore Motor Control Following Contusion Spinal Cord Injury

H Natola - 2017 - search.proquest.com
The central nervous system (CNS) is a unique tissue that is incapable of major repair after
injury. Many CNS disorders have similar injury sequelae including neuronal death, loss of …