The unique structural and functional characteristics of glomerular endothelial cell fenestrations and their potential as a therapeutic target in kidney disease
NC Finch, CR Neal, GI Welsh… - American Journal of …, 2023 - journals.physiology.org
Glomerular endothelial cell (GEnC) fenestrations are a critical component of the glomerular
filtration barrier. Their unique nondiaphragmed structure is key to their function in glomerular …
filtration barrier. Their unique nondiaphragmed structure is key to their function in glomerular …
Activation of angiopoietin-tie2 signaling protects the kidney from ischemic injury by modulation of endothelial-specific pathways
Background Ischemia-reperfusion AKI (IR-AKI) is estimated to affect 2%–7% of all
hospitalized patients. The significant morbidity and mortality associated with AKI indicates …
hospitalized patients. The significant morbidity and mortality associated with AKI indicates …
Targeting lymphatic function in cardiovascular-kidney-metabolic syndrome: preclinical methods to analyze lymphatic function and therapeutic opportunities
JWM Fowler, LJ Song, K Tam… - Frontiers in …, 2024 - frontiersin.org
The lymphatic vascular system spans nearly every organ in the body and serves as an
important network that maintains fluid, metabolite, and immune cell homeostasis. Recently …
important network that maintains fluid, metabolite, and immune cell homeostasis. Recently …
Call for papers: Podocyte physiology and pathophysiology
S Koehler, JH Miner… - American Journal of …, 2023 - journals.physiology.org
This Editorial precedes an upcoming series of research and review articles focused on the
field of podocyte physiology and pathophysiology for which a Call for Papers is being issued …
field of podocyte physiology and pathophysiology for which a Call for Papers is being issued …
VEGFC Overexpression in Kidney Progenitor Cells Is a Model of Renal Lymphangiectasia—Brief Report
BACKGROUND: Lymphangiogenesis is believed to be a protective response in the setting
of multiple forms of kidney injury and mitigates the progression of interstitial fibrosis. To …
of multiple forms of kidney injury and mitigates the progression of interstitial fibrosis. To …
Kidney lymphatics
Following significant advances in lymphatic biology, the important role of kidney lymphatics
in kidney function and dysfunction is now being more fully appreciated. Kidney lymphatics …
in kidney function and dysfunction is now being more fully appreciated. Kidney lymphatics …