Asialoglycoprotein receptor mediated hepatocyte targeting—Strategies and applications

AA D'Souza, PV Devarajan - Journal of controlled release, 2015 - Elsevier
Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …

Main-chain poly (phosphoester) s: History, syntheses, degradation, bio-and flame-retardant applications

KN Bauer, HT Tee, MM Velencoso, FR Wurm - Progress in Polymer …, 2017 - Elsevier
Nature on planet earth is dominated by poly (phosphoester) s (PPEs). They structure and
determine life in the form of deoxy-and ribonucleic acid (DNA & RNA), and, as …

Self-assembly of random copolymers

L Li, K Raghupathi, C Song, P Prasad… - Chemical …, 2014 - pubs.rsc.org
Self-assembly of random copolymers has attracted considerable attention recently. In this
feature article, we highlight the use of random copolymers to prepare nanostructures with …

[HTML][HTML] Main-chain water-soluble polyphosphoesters: Multi-functional polymers as degradable PEG-alternatives for biomedical applications

C Pelosi, MR Tinè, FR Wurm - European polymer journal, 2020 - Elsevier
Polyphosphoesters (PPEs) are a class of (bio) degradable polymers with high chemical
versatility and functionality. In particular, water-soluble PPEs with the phosphoester group in …

Biodegradable polymers for targeted delivery of anti-cancer drugs

S Doppalapudi, A Jain, AJ Domb… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Biodegradable polymers have been used for more than three decades in
cancer treatment and have received increased interest in recent years. A range of …

Positively charged polyprodrug amphiphiles with enhanced drug loading and reactive oxygen species-responsive release ability for traceable synergistic therapy

Y Li, Y Li, W Ji, Z Lu, L Liu, Y Shi, G Ma… - Journal of the American …, 2018 - ACS Publications
Due to the vast differences in chemical properties among small molecule drugs, nucleotide
drugs, and superparamagnetic iron oxide nanocubes (SPIONs), such as charge and …

Advanced biomaterials derived from functional polyphosphoesters: synthesis, properties, and biomedical applications

J Li, Y Hao, H Wang, M Zhang, J He… - ACS Applied Materials & …, 2024 - ACS Publications
Polyphosphoesters (PPEs) represent an innovative class of biodegradable polymers, with
the phosphate ester serving as the core repeating unit of their polymeric backbone …

Development of a theranostic prodrug for colon cancer therapy by combining ligand-targeted delivery and enzyme-stimulated activation

A Sharma, EJ Kim, H Shi, JY Lee, BG Chung, JS Kim - Biomaterials, 2018 - Elsevier
The high incidence of colorectal cancer worldwide is currently a major health concern.
Although conventional chemotherapy and surgery are effective to some extent, there is …

Folic acid and trastuzumab functionalized redox responsive polymersomes for intracellular doxorubicin delivery in breast cancer

SV Lale, A Kumar, S Prasad, AC Bharti… - …, 2015 - ACS Publications
Redox responsive biodegradable polymersomes comprising of poly (ethylene glycol)-
polylactic acid-poly (ethylene glycol)[PEG-ss-PLA-ss-PLA-ss-PEG] triblock copolymer with …

Drug delivery system targeting advanced hepatocellular carcinoma: Current and future

X Zhang, HLH Ng, A Lu, C Lin, L Zhou, G Lin… - … , Biology and Medicine, 2016 - Elsevier
Hepatocellular carcinoma (HCC) has a fairly high morbidity and is notoriously difficult to treat
due to long latent period before detection, multidrug resistance and severe drug-related …