Airway remodeling in chronic obstructive pulmonary disease and asthma: the role of matrix metalloproteinase-9

K Grzela, M Litwiniuk, W Zagorska, T Grzela - Archivum immunologiae et …, 2016 - Springer
Chronic obstructive pulmonary disease (COPD) and asthma are both associated with airflow
restriction and progressive remodeling, which affect the respiratory tract. Among various …

Genes and pathways regulating decline in lung function and airway remodeling in asthma

GY Hur, DH Broide - Allergy, asthma & immunology …, 2019 - synapse.koreamed.org
Asthma is a common disorder of the airways characterized by airway inflammation and by
decline in lung function and airway remodeling in a subset of asthmatics. Airway remodeling …

[HTML][HTML] Baicalein attenuates OVA-induced allergic airway inflammation through the inhibition of the NF-κB signaling pathway

T Xu, X Ge, C Lu, W Dai, H Chen, Z Xiao, L Wu… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Asthma is a type of chronic lung inflammation with restrictions in effective therapy. NF-κB
pathway activation has been suggested to play an important role in the pathogenesis of …

The role of ADAMs in disease pathophysiology

MJ Duffy, E McKiernan, N O'Donovan, PM McGowan - Clinica Chimica Acta, 2009 - Elsevier
The ADAMs are a family of multidomain transmembrane and secreted proteins involved in
both proteolysis and cell adhesion. Altered expression of specific ADAMs is implicated in the …

Epidemiology of virus-induced asthma exacerbations: with special reference to the role of human rhinovirus

T Saraya, D Kurai, H Ishii, A Ito, Y Sasaki… - Frontiers in …, 2014 - frontiersin.org
Viral respiratory infections may be associated with the virus-induced asthma in adults as
well as children. Particularly, human rhinovirus is strongly suggested a major candidate for …

Evaluation of inflammatory markers interleukin-6 (IL-6) and matrix metalloproteinase-9 (MMP-9) in asthma

SP Naik, M PA, J BS, SRV Madhunapantula… - Journal of …, 2017 - Taylor & Francis
Introduction: Even though IL-6 and MMP-9 are associated with airway inflammation in
asthma, there is paucity of data in Indian population. Objective: To determine the levels of IL …

The strong correlation between ADAM33 expression and airway inflammation in chronic obstructive pulmonary disease and candidate for biomarker and treatment of …

M Fachri, M Hatta, MN Massi, A Santoso… - Scientific reports, 2021 - nature.com
Airway inflammation in patients with chronic obstructive pulmonary disease (COPD) is an
amplified response of the normal immune system that occurs as a result of chronic irritation …

Genetic predisposition to chronic obstructive pulmonary disease and/or lung cancer: important considerations when evaluating risk

RA El-Zein, RP Young, RJ Hopkins, CJ Etzel - Cancer prevention research, 2012 - AACR
Chronic obstructive pulmonary disease (COPD) is defined as a disease causing an airflow
limitation that is not fully reversible. COPD is phenotypically complex and characterized by …

Cell therapy with bone marrow mononuclear cells in elastase-induced pulmonary emphysema

N Longhini-dos-Santos, VA Barbosa-de-Oliveira… - Stem Cell Reviews and …, 2013 - Springer
Emphysema is characterized by destruction of alveolar walls with loss of gas exchange
surface and consequent progressive dyspnea. This study aimed to evaluate the efficiency of …

Genetic evidence linking lung cancer and COPD: a new perspective

RP Young, RJ Hopkins, GD Gamble… - The application of …, 2011 - Taylor & Francis
Epidemiological studies indicate that tobacco smoke exposure accounts for nearly 90% of
cases of chronic obstructive pulmonary disease (COPD) and lung cancer. However, genetic …