1. INTRODUCTION The design of organically modified surfaces is a rapidly expanding field
of research in materials science in which the central purpose is access to materials …

The phosphate moiety (PO4-2) is the common structural motif of a wide range of natural
phosphorus-based biologically active compounds, which play important roles as metabolic …

Organophosphorus compounds are important substrates in the study of biochemical
processes, 1 and compounds of tetracoordinate pentavalent phosphorus are widely used as …

Can we consider cancer to be a “metabolic disease”? Tumors are the result of a metabolic
selection, forming tissues composed of heterogeneous cells that generally express an …

This review article surveys recent achievements in the preparation and biological properties
evaluation of fluorinated aminophosphonates and aminophosphonic acids. Recently, in …

A century after their discovery, phosphonates have become important compounds
recognized both for their use as efficient reagents in organic synthesis and for their …

An effective and economical acid-promoted three-component reaction for the construction of
C–P and C–C bonds for the synthesis of γ-ketophosphine oxides with water as the only …

The catalytic enantioselective fluorination and amination of β-keto phosphonates catalyzed
by chiral palladium complexes is described. Treatment of β-keto phosphonates with N …

In the early 1980s, Blackburn and McKenna suggested that α-fluorination might lead to
phosphonates that better mimic natural phosphates. Although α-monofluorination produces …

The distinctive hydrophobic hydration effect in the aqueous solution contributes to the
success of the phospha‐Michael reaction between β‐CF3‐β, β‐disubstituted enones and …