In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …

Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …

Our world is now facing a multitude of novel infectious diseases. Bacterial infections are
treated with antibiotics, albeit with increasing difficulty as many of the more common causes …

Excess iron deposition in the brain often causes oxidative stress-related damage and
necrosis of dopaminergic neurons in the substantia nigra and has been reported to be one …

Nano-sized materials have great potential as drug carriers for nanomedicine applications.
Thanks to their size, they can exploit the cellular machinery to enter cells and be trafficked …

Background Excessive accumulation of reactive oxygen species (ROS) has been
documented as the crucial cellular mechanism of cisplatin-induced ototoxicity. However …

For drug nanocrystals (NCs), particle shapes can affect aqueous solubility, dissolution rate
and oral bioavailability. However, the effects of particle shapes on the transport of NCs …

Solid lipid nanoparticles (SLNs) have been extensively investigated and demonstrated to be
a potential nanocarriers for improving oral bioavailability of many drugs. However, the …

Aim: Asiatic acid (AA) is a promising anticancer agent, however, its delivery to glioblastoma
is a major challenge. This work investigates the beneficial therapeutic efficacy of RGD …