Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Spinal cord repair: advances in biology and technology

G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

Neurostimulation for stroke rehabilitation

WKC Ting, FAR Fadul, S Fecteau… - Frontiers in neuroscience, 2021 - frontiersin.org
Neurological injuries such as strokes can lead to important loss in motor function. Thanks to
neuronal plasticity, some of the lost functionality may be recovered over time. However, the …

Roles of glial ion transporters in brain diseases

S Song, L Luo, B Sun, D Sun - Glia, 2020 - Wiley Online Library
Glial ion transporters are important in regulation of ionic homeostasis, cell volume, and
cellular signal transduction under physiological conditions of the central nervous system …

Functional electrical stimulation and the modulation of the axon regeneration program

JS Jara, S Agger, ER Hollis - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Neural injury in mammals often leads to persistent functional deficits as spontaneous repair
in the peripheral nervous system (PNS) is often incomplete, while endogenous repair …

Targeting sensory and motor integration for recovery of movement after CNS injury

AS Asan, JR McIntosh, JB Carmel - Frontiers in Neuroscience, 2022 - frontiersin.org
The central nervous system (CNS) integrates sensory and motor information to acquire
skilled movements, known as sensory-motor integration (SMI). The reciprocal interaction of …

Spinal cord imaging markers and recovery of volitional leg movement with spinal cord epidural stimulation in individuals with clinically motor complete spinal cord …

E Rejc, AC Smith, KA Weber, B Ugiliweneza… - Frontiers in systems …, 2020 - frontiersin.org
Previous studies have shown that epidural stimulation of the lumbosacral spinal cord (scES)
can re-enable lower limb volitional motor control in individuals with chronic, clinically motor …

[HTML][HTML] Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and the development of hyperreflexia after spinal cord injury in …

DC Malloy, MP Côté - Experimental neurology, 2024 - Elsevier
Spasticity is a complex and multidimensional disorder that impacts nearly 75% of individuals
with spinal cord injury (SCI) and currently lacks adequate treatment options. This …

Spinal cord imaging markers and recovery of standing with epidural stimulation in individuals with clinically motor complete spinal cord injury

AC Smith, CA Angeli, B Ugiliweneza, KA Weber… - Experimental brain …, 2022 - Springer
Spinal cord epidural stimulation (scES) is an intervention to restore motor function in those
with severe spinal cord injury (SCI). Spinal cord lesion characteristics assessed via …

Independent replication of motor cortex and cervical spinal cord electrical stimulation to promote forelimb motor function after spinal cord injury in rats

Q Yang, A Ramamurthy, S Lall, J Santos… - Experimental …, 2019 - Elsevier
Cervical spinal cord injury (SCI) impairs arm and hand function largely by interrupting
descending tracts. Most SCI spare some axons at the lesion, including the corticospinal tract …