The lipid biochemistry of eukaryotic algae

Y Li-Beisson, JJ Thelen, E Fedosejevs… - Progress in Lipid …, 2019 - Elsevier
Algal lipid metabolism fascinates both scientists and entrepreneurs due to the large diversity
of fatty acyl structures that algae produce. Algae have therefore long been studied as …

Genetic engineering of microalgae for enhanced lipid production

CF Muñoz, C Südfeld, MIS Naduthodi… - Biotechnology …, 2021 - Elsevier
Microalgae have the potential to become microbial cell factories for lipid production. Their
ability to convert sunlight and CO 2 into valuable lipid compounds has attracted interest from …

CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii

SE Shin, JM Lim, HG Koh, EK Kim, NK Kang, S Jeon… - Scientific reports, 2016 - nature.com
Genome editing is crucial for genetic engineering of organisms for improved traits,
particularly in microalgae due to the urgent necessity for the next generation biofuel …

[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control

G Chen, JL Harwood, MJ Lemieux, SJ Stone… - Progress in Lipid …, 2022 - Elsevier
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

Regulatory mechanisms of lipid biosynthesis in microalgae

H Chen, Q Wang - Biological Reviews, 2021 - Wiley Online Library
Microalgal lipids are highly promising feedstocks for biofuel production. Microalgal lipids,
especially triacylglycerol, and practical applications of these compounds have received …

An Indexed, Mapped Mutant Library Enables Reverse Genetics Studies of Biological Processes in Chlamydomonas reinhardtii

X Li, R Zhang, W Patena, SS Gang, SR Blum… - The Plant …, 2016 - academic.oup.com
The green alga Chlamydomonas reinhardtii is a leading unicellular model for dissecting
biological processes in photosynthetic eukaryotes. However, its usefulness has been limited …

Lipid Production from Nannochloropsis

XN Ma, TP Chen, B Yang, J Liu, F Chen - Marine drugs, 2016 - mdpi.com
Microalgae are sunlight-driven green cell factories for the production of potential bioactive
products and biofuels. Nannochloropsis represents a genus of marine microalgae with high …

Metabolic engineering of lipid catabolism increases microalgal lipid accumulation without compromising growth

EM Trentacoste, RP Shrestha… - Proceedings of the …, 2013 - National Acad Sciences
Biologically derived fuels are viable alternatives to traditional fossil fuels, and microalgae
are a particularly promising source, but improvements are required throughout the …

Spatial metabolomics of in situ host–microbe interactions at the micrometre scale

B Geier, EM Sogin, D Michellod, M Janda… - Nature …, 2020 - nature.com
Spatial metabolomics describes the location and chemistry of small molecules involved in
metabolic phenotypes, defence molecules and chemical interactions in natural communities …

Choreography of Transcriptomes and Lipidomes of Nannochloropsis Reveals the Mechanisms of Oil Synthesis in Microalgae

J Li, D Han, D Wang, K Ning, J Jia, L Wei, X Jing… - The Plant …, 2014 - academic.oup.com
To reveal the molecular mechanisms of oleaginousness in microalgae, transcriptomic and
lipidomic dynamics of the oleaginous microalga Nannochloropsis oceanica IMET1 under …