Stem cells: innovative therapeutic options for neurodegenerative diseases?
G Bonaventura, A Munafò, CM Bellanca, V La Cognata… - Cells, 2021 - mdpi.com
Neurodegenerative diseases are characterized by the progressive loss of structure and/or
function of both neurons and glial cells, leading to different degrees of pathology and loss of …
function of both neurons and glial cells, leading to different degrees of pathology and loss of …
Inflammation-Mediated Responses in the Development of Neurodegenerative Diseases
Since its first description over a century ago, neurodegenerative diseases (NDDs) have
impaired the lives of millions of people worldwide. As one of the major threats to human …
impaired the lives of millions of people worldwide. As one of the major threats to human …
Myt1l induced direct reprogramming of pericytes into cholinergic neurons
Objective The cholinergic deficit is thought to underlie progressed cognitive decline in
Alzheimer Disease. The lineage reprogramming of somatic cells into cholinergic neurons …
Alzheimer Disease. The lineage reprogramming of somatic cells into cholinergic neurons …
Small molecular compounds efficiently convert human fibroblasts directly into neurons
J Yang, H Cao, S Guo, H Zhu… - Molecular …, 2020 - spandidos-publications.com
No effective treatment is currently available for neurodegenerative diseases, and existing
pharmacotherapy is inconsistent with severe side effects. Cell replacement therapy is …
pharmacotherapy is inconsistent with severe side effects. Cell replacement therapy is …
Pharmacological Notch pathway inhibition leads to cell cycle arrest and stimulates ascl1 and neurogenin2 genes expression in dental pulp stem cells-derived …
A Niapour, H Ghasemi Hamidabadi, N Niapour… - Biotechnology …, 2019 - Springer
Objective Human dental pulp-derived stem cells (hDPSCs) are becoming an attractive
source for cell-based neurorestorative therapies. As such, it is important to understand the …
source for cell-based neurorestorative therapies. As such, it is important to understand the …
Stem cells in Alzheimer's disease: current standing and future challenges
To date, there is no definitive treatment for Alzheimer's disease (AD). The realm of stem cells
is very promising in regenerative medicine, particularly for neurodegenerative diseases …
is very promising in regenerative medicine, particularly for neurodegenerative diseases …
Moving from the dish to the clinical practice: a decade of lessons and perspectives from the pre-clinical and clinical stem cell studies for Alzheimer's disease
To date, there is no definitive treatment for Alzheimer's disease (AD). The realm of stem cells
is very promising in regenerative medicine, particularly neurodegenerative disorders …
is very promising in regenerative medicine, particularly neurodegenerative disorders …
Challenges to international stem cell clinical trials in countries with diverging regulations
A Rosemann - Safety, ethics and regulations, 2017 - Springer
This chapter addresses challenges to the organization and conduct of international stem cell
clinical trials in a context of regulatory pluralism. Multi-country clinical trial collaborations in …
clinical trials in a context of regulatory pluralism. Multi-country clinical trial collaborations in …
[PDF][PDF] Treatment of Parkinson's disease using human stem cells
C Palmer, R Coronel, I Liste - J. Stem Cell Res. Med., 2016 - siriusstore.com
The progressive loss of dopamine neurons (DAn) in the substantia nigra is the main
characteristic of Parkinson's disease (PD), the second most common neurodegenerative …
characteristic of Parkinson's disease (PD), the second most common neurodegenerative …